Skip to main content

Mechanisms of DNA Methylation and Demethylation

Guest Editor:
Albert Jeltsch, PhD, University of Stuttgart, Germany

Submission Status: Open   |   Submission Deadline: 31 January 2025



New Content ItemEpigenetics & Chromatin is calling for submissions to our new Collection on "Mechanisms of DNA Methylation and Demethylation". This Collection aims to bring together cutting-edge research elucidating the molecular mechanisms, regulatory pathways, and functional implications of DNA methylation and demethylation.


Image credit: ktsdesign / Stock.adobe.com

About the collection

We invite submissions dedicated to exploring the intricate mechanisms underlying DNA methylation and demethylation processes. DNA methylation, catalyzed by DNA methyltransferases, plays a pivotal role in gene regulation and genome stability. Conversely, DNA demethylation mechanisms, whether passive or active, are essential for gene activation and dynamic gene expression patterns. This Collection aims to bring together cutting-edge research elucidating the molecular mechanisms, regulatory pathways, and functional implications of DNA methylation and demethylation. We encourage contributions spanning experimental, computational, and theoretical approaches.

Topics to include:

• Role of DNA methyltransferases in methylation patterning
• Mechanisms of passive and active DNA demethylation
• Regulation of DNA methylation dynamics during development and disease
• Interplay between DNA methylation and histone modifications
• Computational modeling and simulation of DNA methylation dynamics
• Technological advancements in profiling DNA methylation and demethylation
• Therapeutic targeting of DNA methylation for disease intervention
• Evolutionary perspectives on the conservation and divergence of DNA methylation pathways

There are currently no articles in this collection.

Submission Guidelines

Back to top

Before submitting your manuscript, please ensure you have read our submission guidelines. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Mechanisms of DNA Methylation and Demethylation" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Guest Editor has no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests.