In this Collection we aim to explore two thematic areas: Lipids in Reproductive Diseases in Women and Influence of Gender Bias on Recent Lipid Studies.
Lipids in Reproductive Diseases in Women
Lipids play a crucial role in the pathophysiology of reproductive diseases in women, serving as key modulators of hormonal balance, inflammation and cellular signaling pathways. This Collection will investigate the complex relationship between lipids and reproductive health, examining their impact on conditions such as polycystic ovary syndrome (PCOS), endometriosis, and infertility. Recent research has provided valuable insights into how lipid metabolism affects women’s reproductive physiology, from dyslipidemia-associated comorbidities to the role of lipid mediators in modulating reproductive tissue function. This Collection aims to pave the way for novel therapeutic intervention and personalized approaches to women’s health.
Influence of Gender Bias on Recent Lipid Studies
Recent advancement in lipids and women’s health research have shed light on the intricate interplay between lipid metabolism and various disease states. However, the influence of gender bias continues to shape lipid research in women’s health. This Collection aims to dissect the impact of gender bias on recent lipid studies. From underrepresentation of women in lipid research cohorts to gender disparities in the evaluation and management of lipid-related diseases, such as cardiovascular disease and metabolic syndrome, sexual bias poses a threat to our understanding of lipid metabolism and its implications for women’s health. By promoting a more equitable and inclusive approach to lipid research, this edition aims to improve our ability to prevent, diagnose, and treat lipid-related diseases in women.
We welcome articles including original articles, systematic reviews, and meta-analyses on these two thematic areas.
Keywords: lipid metabolism, women’s health, reproductive diseases, lipid-related diseases
The topics of interest include but not limited to:
• Understanding the role of lipids in reproductive health and disease in women.
• Understanding of sex-specific differences in lipid-related diseases pathogenesis.
• The development of novel therapeutic interventions targeting lipid metabolism and signaling pathways for the treatment of reproductive diseases and lipid-related diseases and associated comorbidities in women.
• Lipidomics and metabolomics approaches in understanding reproductive diseases in women.
• Epigenetic regulation of lipid metabolism in reproductive diseases.
• Role of gut microbiota and its metabolites in modulating lipid metabolism in metabolic and reproductive function.
• Impact of dietary lipids on metabolic and reproductive health outcomes in women.
Questions to be answered:
• How do lipids contribute to the pathophysiology of reproductive diseases in women?
• What are the mechanisms by which dyslipidemia affects hormonal balance, inflammation, and cellular signaling pathways in women's reproductive health?
• How do lipid mediators modulate the function of reproductive tissues, and what implications does this have for disease development and progression?
• What sex-specific differences exist in the pathogenesis of lipid-related diseases, and how do these differences influence disease presentation, diagnosis, and treatment in women?
