Immune regulation for iPSC-based transplantation

Possible NK cell-mediated immune responses against iPSC-derived cells in allogeneic transplantation settings

In the regenerative medicine field, allogenic transplantation of regenerated tissues has been promoted because autologous transplantation setting is costly and time-consuming to prepare and therefore unsuitabl...

Authors: Kyoko Masuda and Hiroshi Kawamoto

Citation: Inflammation and Regeneration 2021 41:2

Content type: Review Published on: 6 January 2021
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Current status and future perspectives of HLA-edited induced pluripotent stem cells

In 2007, Human-induced pluripotent stem cells (iPSCs) were generated by transducing four genes (Oct3/4, Sox2, Klf4, c-Myc). Because iPSCs can differentiate into any types of cells in the body and have fewer et...

Authors: Keiko Koga, Bo Wang and Shin Kaneko

Citation: Inflammation and Regeneration 2020 40:23

Content type: Review Published on: 1 October 2020
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Strategies for immune regulation in iPS cell-based cardiac regenerative medicine

Cardiac regenerative therapy is expected to be a promising therapeutic option for the treatment of severe cardiovascular diseases. Artificial tissues or organoids made from cardiovascular cell lineages differe...

Authors: Kozue Murata, Masaya Ikegawa, Kenji Minatoya and Hidetoshi Masumoto

Citation: Inflammation and Regeneration 2020 40:36

Content type: Review Published on: 29 September 2020
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Immune reaction and regulation in transplantation based on pluripotent stem cell technology

The development of pluripotent stem cell (PSC)-based technologies provides us a new therapeutic approach that generates grafts for transplantation. In order to minimize the risk of immune reaction, the banking...

Authors: Ryo Otsuka, Haruka Wada, Tomoki Murata and Ken-ichiro Seino

Citation: Inflammation and Regeneration 2020 40:12

Content type: Review Published on: 1 July 2020
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Immune regulation for iPSC-based transplantation

Possible NK cell-mediated immune responses against iPSC-derived cells in allogeneic transplantation settings

Current status and future perspectives of HLA-edited induced pluripotent stem cells

Strategies for immune regulation in iPS cell-based cardiac regenerative medicine

Immune reaction and regulation in transplantation based on pluripotent stem cell technology