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Call for papers - Immunology and immunotherapy in solid cancers

Guest Editors:
Zachary C. Hartman: Duke University, United States
Daniel Smrz: Charles University and Motol University Hospital, Czech Republic

Submission Status: Open   |   Submission Deadline: 29 May 2024

BMC Cancer is calling for submissions to our Collection on the role of the immune tumor microenvironment and advances in immunotherapy approaches in solid tumors. This Collection intends to highlight innovative new research on cancer vaccines, immune checkpoint inhibition, and solid tumor resistance, inflammation, and microenvironment immunosuppression, while also delving into alternative immune treatments, as well as combinatorial approaches with standard therapies and cellular therapies.

New Content ItemThis collection supports and amplifies research related to Sustainable Development Goal 3: Good Health & Wellbeing (SDG3).

Meet the Guest Editors

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Zachary C. Hartman: Duke University, United States

Dr Zachary C. Hartman is an Associate Professor at Duke University in the Departments of Surgery, Pathology, and Integrative Immunology and the Director of the Center for Applied Therapeutics. He received his PhD in Genetics and Genomics from Duke University and did post-doctoral fellowships at Duke and the MD Anderson Cancer Center. In 2012, he returned to Duke and developed a laboratory focused on the study of immunity and inflammation in cancer, spanning the use of novel immunotherapeutic agents, investigation of tumor-targeting antibodies, and development of vaccines to specific oncogenic targets, which are currently in clinical trials at Duke. 

Daniel Smrz: Charles University and Motol University Hospital, Czech Republic

Daniel Smrz is a leader of the Tumor Immunology and Immunotherapy Group at the Department of Immunology at Charles University, Second Faculty of Medicine, and the Motol University Hospital in Prague. He is also a vice-director of the Laboratory of Immunotherapy at the Institute of Microbiology of the Czech Academy of Sciences, v. v. i., in Prague. He has a chemistry, biochemistry, molecular biology, and immunology background. His team dedicates to researching immune cells and their use for cancer immunotherapy. A long-term goal of his team is an in-depth understanding of the tumoral/paratumoral immune microenvironment and the introduction of new technologies for in vitro generation of immune cells for adoptive cell immunotherapy of cancer.

About the Collection

BMC Cancer is calling for submissions to our Collection on immunology and immunotherapy in solid cancers.

While surgery, chemotherapy, and radiation therapy have been the standard of care for solid cancer treatment for decades, these methods have often proved unable to provide durable disease control. Thus, immunotherapy could be the next core pillar in solid tumor treatment. However, clinical success with immunotherapy for solid tumors has often been very difficult to achieve due to several barriers, including immunosuppressive tumor microenvironment, inefficient trafficking, and heterogeneity of tumor antigens. A better understanding of the immune system and identifying new molecular targets would foster the development of novel, safe, and effective treatments for solid cancers. 

In recognition of this relevant field, BMC Cancer has launched this Collection which encourages submissions addressing topics including, but not limited to:
•    Cancer vaccines
•    Immune checkpoint inhibition
•    Investigations into mechanisms of immunosuppression in the tumor microenvironment
•    Alternative immune mechanisms for treatment
•    Immune modulatory combinations with standard-of-care therapies
•    Cellular therapies and CAR T-Cells
•    Innate and adaptive immune responses in cancer
•    Impact of stromal population on cancer immunity and immunotherapy
•    Solid tumor resistance to cell-based therapies
•    Inflammation in the tumor and peritumoral microenvironment

Image credit: Juan Gärtner /

There are currently no articles in this collection.

Submission Guidelines

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This Collection welcomes submission of original Research Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Immunology and immunotherapy in solid cancers" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.