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Elimination of neglected tropical diseases

Guest edited by Robert Bergquist, Adrian Hopkins and Xiao-Nong Zhou

An article collection published in Infectious Diseases of Poverty.

New Content ItemInspired by the 'roadmap' developed by the World Health Organization (WHO) in 2011 for the control, elimination and eradication of a group of infectious diseases named neglected tropical diseases (NTDs), senior government officials from endemic and donor countries, global health organizations, major pharmaceutical companies, Bill Gates of the Bill & Melinda Gates Foundation and WHO's then Director General Margaret Chan signed the London Declaration in January 2012, a commitment to control or eliminate 10 diseases by the end of this decade. This joint effort to do something about infections strongly associated with poverty in tropical and subtropical environments, was endorsed by all member states through the World Health Assembly (WHA) NTD resolution (1948-2013) in 2013 and has since become the largest public health initiatives in history. Eliminate NTDs is indeed one of indicators listed in the United Nation’s Sustainable Development Goal (2015-2030), which is linked with a crucial component of universal health coverage aiming to lift the burden of disease from populations in low-income and middle-income countries with limited access to health services and conceptualized as “leaving no one behind”.

Stakeholders have chartered a course toward health and sustainability among the world’s poorest communities offering them global eradication of dracunculiasis, blinding trachoma, leprosy, human African trypanosomiasis, lymphatic filariasis and elimination at the regional level of rabies, endemic treponematoses (endemic syphilis, pinta and yaws), Chagas disease, visceral leishmaniasis, onchocerciasis and schistosomiasis by 2020. However, the fourth progress report from Uniting to Combat Neglected Tropical Diseases issued in 2016 finds that many deadlines have been missed. Still there is hope that the above mentioned five NTDs could be eliminated or eradicated within the next few years with continued significant gains for the other NTDs. On the other hand, for roughly an equal number of diseases (trichuriasis, hookworm disease, food-borne trematodiases, cystic echinococcosis) progress has been minimal or stalled. In some cases, we are losing ground, especially for some of the vector-borne and zoonotic diseases, including dengue and other arbovirus infections, leishmaniasis, Chagas disease.

This intention of this issue is to show the progress and challenges in NTD elimination in different geographic settings around the world giving the current status and prospects for each disease. Particularly, some of successive stories will be published to share experiences with other counties or regions in order to promote the global elimination program on NTDs. 

  1. Content type: Research Article

    Lymphatic filariasis is endemic in nine of the eleven Member States of the World Health Organization South East Asia Region. This article describes the intensive interventions with the National Programme for E...

    Authors: Sunsanee Rojanapanus, Tanaporn Toothong, Patcharida Boondej, Suwich Thammapalo, Naraporn Khuanyoung, Weena Santabutr, Preecha Prempree, Deyer Gopinath and Kapa D. Ramaiah

    Citation: Infectious Diseases of Poverty 2019 8:38

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    The Correction to this article has been published in Infectious Diseases of Poverty 2019 8:72

  2. Content type: Scoping Review

    Helminths are endemic in more than half of the world’s countries, raising serious public health concerns. Accurate diagnosis of helminth infection is crucial to control strategies. Traditional parasitological ...

    Authors: Miao-Han Deng, Lan-Yi Zhong, Okanurak Kamolnetr, Yanin Limpanont and Zhi-Yue Lv

    Citation: Infectious Diseases of Poverty 2019 8:20

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  3. Content type: Research Article

    Snail control is an important component in the national schistosomiasis control programme in China, by application of chemical molluscicides, forestry projects, agriculture projects and water conservancy proje...

    Authors: Xiao Yang, Yi Zhang, Qi-Xiang Sun, Jin-Xing Zhou and Xiao-Nong Zhou

    Citation: Infectious Diseases of Poverty 2019 8:13

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  4. Content type: Research Article

    The recent development of rapid diagnostic tests (RDTs) for human African trypanosomiasis (HAT) enables elimination programmes to decentralise serological screening services to frontline health facilities. How...

    Authors: Shona J. Lee and Jennifer J. Palmer

    Citation: Infectious Diseases of Poverty 2018 7:84

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  5. Content type: Short Report

    Schistosomiasis and soil-transmitted helminthiasis (STH) are endemic diseases in Burundi. STH control is integrated into health facilities (HF) across the country, but schistosomiasis control is not. The prese...

    Authors: Paul Bizimana, Katja Polman, Jean-Pierre Van Geertruyden, Frédéric Nsabiyumva, Céline Ngenzebuhoro, Elvis Muhimpundu and Giuseppina Ortu

    Citation: Infectious Diseases of Poverty 2018 7:66

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  6. Content type: Research Article

    The prevalence of schistosomiasis japonica has decreased significantly, and the responses changing from control to elimination in Jiangsu Province, P.R. China. How to estimate the change in prevalence of schis...

    Authors: Xin-Yao Wang, Jing Xu, Song Zhao, Wei Li, Jian-Feng Zhang, Jian He, Ashley M. Swing and Kun Yang

    Citation: Infectious Diseases of Poverty 2018 7:62

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  7. Content type: Research Article

    Lymphatic filariasis (LF) is endemic in Myanmar and targeted for elimination. To highlight the National Programme to Eliminate Lymphatic Filariasis (NPELF) progress between 2000 and 2014, this paper describes ...

    Authors: Ni Ni Aye, Zaw Lin, Khin Nan Lon, Nay Yi Yi Linn, Thet Wai Nwe, Khin Mon Mon, Kapa Ramaiah, Hannah Betts and Louise A. Kelly-Hope

    Citation: Infectious Diseases of Poverty 2018 7:56

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  8. Content type: Research Article

    Endemicity of lymphatic filariasis (LF) in Cambodia was proven in 1956 when microfilariae were detected in mosquitos in the Kratié province. In 2001, an extensive study confirmed the presence of both Brugia malay...

    Authors: Virak Khieu, Vandine Or, Chhakda Tep, Peter Odermatt, Reiko Tsuyuoka, Meng Chuor Char, Molly A. Brady, Joshua Sidwell, Aya Yajima, Rekol Huy, Kapa D. Ramaiah and Sinuon Muth

    Citation: Infectious Diseases of Poverty 2018 7:15

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  9. Content type: Scoping Review

    Historically, the target in the schistosomiasis control has shifted from infection to morbidity, then back to infection, but now as a public health problem, before moving on to transmission control. Currently,...

    Authors: Robert Bergquist, Xiao-Nong Zhou, David Rollinson, Jutta Reinhard-Rupp and Katharina Klohe

    Citation: Infectious Diseases of Poverty 2017 6:158

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  10. Content type: Research Article

    Neglected tropical diseases (NTDs) prevail in conditions of poverty and contribute to the maintenance of social inequality. Out of the NTDs prioritized by the Brazilian Ministry of Health, four parasitic infec...

    Authors: Eduardo Brandão, Sebastián Romero, Maria Almerice Lopes da Silva and Fred Luciano Neves Santos

    Citation: Infectious Diseases of Poverty 2017 6:154

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  11. Content type: Opinion

    Remarkable progress has been made in the fight against neglected tropical diseases, but new challenges have emerged. Innovative diagnostics, better drugs and new insecticides are often identified as the priori...

    Authors: Giuseppina Ortu and Oliver Williams

    Citation: Infectious Diseases of Poverty 2017 6:147

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