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Ion beam therapy – Results from a clinical research group at the Heidelberg Ion Beam Therapy Center

New Content Item (4)Guest Edited by Prof. Oliver Jäkel

Radiotherapy with heavy charged particles has been pioneered by Heidelberg University in the last 20 years. Starting in 1997, scanned carbon ions were explored for radiotherapy at the GSI Helmholtz Centre for Heavy Ion Research and since 2009, at the Heidelberg Ion Beam Therapy Center (HIT) at the University Hospital Heidelberg. At HIT, proton and carbon ions have been used for treatments of more than 4000 patients until mid-2017. Currently helium and oxygen ions are investigated in preclinical research projects.  The German Research Foundation (Deutsche Forschungsgemeinschaft, DFG) has funded preclinical and clinical research at HIT within a clinical research group for many years.

This special issue published in Radiation Oncology summarizes some of the highlights of this research group and gathers articles from the field of medical physics and radiobiology, as well as clinical results for a variety of tumor entities.  The main focus is on the effects of organ motion in scanned beam delivery, the radiobiological effectiveness of light ion beams and biomarkers applied.  The clinical application addresses tumors of the brain, skull base and lung, as well as hepatic and pancreatic tumors.

  1. Content type: Research

    To summarize the research activities of the “clinical research group heavy ion therapy”, funded by the German Research Foundation (DFG, KFO 214), on the impact of intrinsic tumor characteristics (grading, hypo...

    Authors: Christin Glowa, Peter Peschke, Stephan Brons, Oliver C. Neels, Klaus Kopka, Jürgen Debus and Christian P. Karger

    Citation: Radiation Oncology 2017 12:174

    Published on:

  2. Content type: Review

    Scanned ion beam therapy has special demands for treatment of intra-fractionally moving tumors such as lesions in lung or liver. Interplay effects between beam and organ motion can in those settings lead to un...

    Authors: Christoph Bert and Klaus Herfarth

    Citation: Radiation Oncology 2017 12:170

    Published on:

  3. Content type: Research

    For irradiation treatment planning of meningiomas the use of PET-scans is well established. The most frequently used tracers are either based on amino acids or the somatostatin receptor ligand DOTATOC. Since u...

    Authors: Jan Oliver Dittmar, Clemens Kratochwil, Anne Dittmar, Thomas Welzel, Daniel Habermehl, Stefan Rieken, Frederik L. Giesel, Uwe Haberkorn, Jürgen Debus and Stephanie E. Combs

    Citation: Radiation Oncology 2017 12:169

    Published on:

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