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Hydrocephalus: Promoting research for improved outcomes

This collection is a series of articles published in Fluids and Barriers of the CNS by members of the International Society for Hydrocephalus and Cerebrospinal Fluid Disorders. This series is headed by two commissioned task force reviews (Vinchon et al.; Malm et al.) reporting important research into hydrocephalus and aiming to stimulate future research, with the particular objective of improving the quality of life for patients.

This collection of articles has not been sponsored and articles have undergone the journal’s standard peer-review process.

  1. Content type: Research

    The objective was to identify changes in quantitative MRI measures in patients with idiopathic normal pressure hydrocephalus (iNPH) occurring in common after oral acetazolamide (ACZ) and external lumbar draina...

    Authors: Milos Ivkovic, Martin Reiss-Zimmermann, Heather Katzen, Matthias Preuss, Ilhami Kovanlikaya, Linda Heier, Noam Alperin, Karl T Hoffmann and Norman Relkin

    Citation: Fluids and Barriers of the CNS 2015 12:9

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  2. Content type: Research

    Normal pressure hydrocephalus (NPH) is most common in the elderly and has a high co-morbidity with Alzheimer’s disease (AD) and cerebrovascular disease (CVD). To understand the relationship between NPH, AD and...

    Authors: Gerald D Silverberg, Miles C Miller, Crissey L Pascale, Ilias N Caralopoulos, Yuksel Agca, Cansu Agca and Edward G Stopa

    Citation: Fluids and Barriers of the CNS 2015 12:2

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  3. Content type: Research

    A tool for standardized and repeated neuropsychological assessments in patients with idiopathic normal pressure hydrocephalus (INPH) is needed. The objective of this study was to develop a computerized neurops...

    Authors: Anders Behrens, Anders Eklund, Eva Elgh, Cynthia Smith, Michael A Williams and Jan Malm

    Citation: Fluids and Barriers of the CNS 2014 11:22

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  4. Content type: Short paper

    Idiopathic normal pressure hydrocephalus (iNPH) is one of few types of dementia that can be treated with shunt surgery and cerebrospinal fluid (CSF) diversion. It is frequently present with cerebral vasculopat...

    Authors: Per Kristian Eide and Are Hugo Pripp

    Citation: Fluids and Barriers of the CNS 2014 11:19

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  5. Content type: Research

    The lack of absorption of CSF at the vertex in chronic hydrocephalus has been ascribed to an elevation in the arachnoid granulation outflow resistance (Rout). The CSF infusion studies measuring Rout are dependent...

    Authors: Grant A Bateman and Sabbir H Siddique

    Citation: Fluids and Barriers of the CNS 2014 11:11

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  6. Content type: Review

    According to the traditional understanding of cerebrospinal fluid (CSF) physiology, the majority of CSF is produced by the choroid plexus, circulates through the ventricles, the cisterns, and the subarachnoid ...

    Authors: Thomas Brinker, Edward Stopa, John Morrison and Petra Klinge

    Citation: Fluids and Barriers of the CNS 2014 11:10

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  7. Content type: Research

    Idiopathic normal pressure hydrocephalus (iNPH) is a treatable cause of dementia, gait disturbance, and urinary incontinence in elderly patients with ventriculomegaly. Its unique morphological feature, called ...

    Authors: Namiko Nishida, Nanae Nagata, Hiroki Toda, Naoto Jingami, Kengo Uemura, Akihiko Ozaki, Mitsuhito Mase, Yoshihiro Urade, Sadayuki Matsumoto, Koichi Iwasaki and Masatsune Ishikawa

    Citation: Fluids and Barriers of the CNS 2014 11:9

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  8. Content type: Review

    Idiopathic normal pressure hydrocephalus (INPH) is a syndrome of ventriculomegaly, gait impairment, cognitive decline and incontinence that occurs in an elderly population prone to many types of comorbidities....

    Authors: Jan Malm, Neill R Graff-Radford, Masatsune Ishikawa, Bo Kristensen, Ville Leinonen, Etsuro Mori, Brian K Owler, Mats Tullberg, Michael A Williams and Norman R Relkin

    Citation: Fluids and Barriers of the CNS 2013 10:22

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  9. Content type: Review

    The outcome of pediatric hydrocephalus, including surgical complications, neurological sequelae and academic achievement, has been the matter of many studies. However, much uncertainty remains, regarding the v...

    Authors: Matthieu Vinchon, Harold Rekate and Abhaya V Kulkarni

    Citation: Fluids and Barriers of the CNS 2012 9:18

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