Skip to main content


Hot topics

Edited by Francesco Marincola

The Journal of Translational Medicine is excited to launch the Hot topics series, which will publish a limited number of high interest review articles per year, focussing on cutting edge topics from across the breadth of the journal’s scope. Articles will cover emerging concepts and points of view or foresights, rather than focusing on comprehensive discussions of well-established areas. We encourage the participation of investigators from different groups with complementary expertise in the proposed theme.

Articles should be submitted by invitation of Editor-in-Chief, Francesco Marincola, only, and will be published in the series free of charge. If you would like to propose a review article for the Hot Topics series, please contact Dr Marincola at with a suggested outline.

Published articles have undergone the journal's standard peer-review process overseen by the Editor-in-Chief, who declares no competing interests.

  1. Review

    Molecular targeting in acute myeloid leukemia

    Acute myeloid leukemia (AML) is a heterogenous disease associated with distinct genetic and molecular abnormalities. Somatic mutations result in dysregulation of intracellular signaling pathways, epigenetics, ...

    Seah H. Lim, Patrycja M. Dubielecka and Vikram M. Raghunathan

    Journal of Translational Medicine 2017 15:183

    Published on: 29 August 2017

  2. Review

    Molecular imaging biomarkers for cell-based immunotherapies

    While many decades of scientific research studies have gone into harnessing the power of the immune system to fight cancer, only recently have cancer immunotherapeutic approaches begun to show robust clinical ...

    Mohammad Haris, Puneet Bagga, Hari Hariharan, Bevin McGettigan-Croce, Laura A. Johnson and Ravinder Reddy

    Journal of Translational Medicine 2017 15:140

    Published on: 19 June 2017

  3. Review

    State of play and clinical prospects of antibody gene transfer

    Recombinant monoclonal antibodies (mAbs) are one of today’s most successful therapeutic classes in inflammatory diseases and oncology. A wider accessibility and implementation, however, is hampered by the high...

    Kevin Hollevoet and Paul J. Declerck

    Journal of Translational Medicine 2017 15:131

    Published on: 7 June 2017

  4. Review

    The role of vitamin C in the treatment of pain: new insights

    The vitamin C deficiency disease scurvy is characterised by musculoskeletal pain and recent epidemiological evidence has indicated an association between suboptimal vitamin C status and spinal pain. Furthermor...

    Anitra C. Carr and Cate McCall

    Journal of Translational Medicine 2017 15:77

    Published on: 14 April 2017