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Hot topics

Edited by Francesco Marincola

The Journal of Translational Medicine is excited to launch the Hot topics series, which will publish a limited number of high interest review articles per year, focussing on cutting edge topics from across the breadth of the journal’s scope. Articles will cover emerging concepts and points of view or foresights, rather than focusing on comprehensive discussions of well-established areas. We encourage the participation of investigators from different groups with complementary expertise in the proposed theme.

Articles should be submitted by invitation of Editor-in-Chief, Francesco Marincola, only, and will be published in the series free of charge. If you would like to propose a review article for the Hot Topics series, please contact Dr Marincola at jtransmed@biomedcentral.com with a suggested outline.

Published articles have undergone the journal's standard peer-review process overseen by the Editor-in-Chief, who declares no competing interests.

  1. Content type: Review

    Acute myeloid leukemia (AML) is a heterogenous disease associated with distinct genetic and molecular abnormalities. Somatic mutations result in dysregulation of intracellular signaling pathways, epigenetics, ...

    Authors: Seah H. Lim, Patrycja M. Dubielecka and Vikram M. Raghunathan

    Citation: Journal of Translational Medicine 2017 15:183

    Published on:

  2. Content type: Review

    Immunotherapy consists of activating the patient’s immune system to fight cancer and has the great potential of preventing future relapses thanks to immunological memory. A great variety of strategies have eme...

    Authors: Michele Graciotti, Cristiana Berti, Harm-Anton Klok and Lana Kandalaft

    Citation: Journal of Translational Medicine 2017 15:142

    Published on:

  3. Content type: Review

    While many decades of scientific research studies have gone into harnessing the power of the immune system to fight cancer, only recently have cancer immunotherapeutic approaches begun to show robust clinical ...

    Authors: Mohammad Haris, Puneet Bagga, Hari Hariharan, Bevin McGettigan-Croce, Laura A. Johnson and Ravinder Reddy

    Citation: Journal of Translational Medicine 2017 15:140

    Published on:

  4. Content type: Review

    Recombinant monoclonal antibodies (mAbs) are one of today’s most successful therapeutic classes in inflammatory diseases and oncology. A wider accessibility and implementation, however, is hampered by the high...

    Authors: Kevin Hollevoet and Paul J. Declerck

    Citation: Journal of Translational Medicine 2017 15:131

    Published on:

  5. Content type: Review

    The vitamin C deficiency disease scurvy is characterised by musculoskeletal pain and recent epidemiological evidence has indicated an association between suboptimal vitamin C status and spinal pain. Furthermor...

    Authors: Anitra C. Carr and Cate McCall

    Citation: Journal of Translational Medicine 2017 15:77

    Published on:

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