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Gene regulation tools for treating genetic diseases and cancers based on CRISPR-related technologies

Guest Editor:
Yuchen Liu: The First Affiliated Hospital of Shenzhen University, China

Submission Status: Open   |   Submission Deadline: 30 April 2024


Cellular & Molecular Biology Letters is calling for submissions to our Collection on Gene regulation tools for treating genetic diseases and cancers based on CRISPR-related technologies.

About the collection

CRISPR-related technologies have emerged as powerful tools for editing and manipulating genes, and have revolutionized the field of gene therapy. This Collection aims to highlight the latest research and developments in this field, with a focus on the regulatory tools used to treat genetic diseases and cancers. Specifically, the Collection will cover the following topics:

- Overview of CRISPR-related technologies for gene regulation

- CRISPR-based gene editing tools for treating genetic diseases and cancers

- Non-editing CRISPR-based gene regulation tools for treating genetic diseases and cancers

- Clinical applications of CRISPR-based gene regulation tools

- Ethical and societal implications of CRISPR-based gene regulation tools

  1. Bladder cancer (BCa) ranks among the predominant malignancies affecting the urinary system. Cisplatin (CDDP) remains a cornerstone therapeutic agent for BCa management. Recent insights suggest pivotal roles of...

    Authors: Congjie Xu, Jiaquan Zhou, Xiaoting Zhang, Xinli Kang, Shuan Liu, Mi Song, Cheng Chang, Youtu Lin and Yang Wang
    Citation: Cellular & Molecular Biology Letters 2024 29:28
  2. Despite notable advancements in the investigation and management of lung adenocarcinoma (LUAD), the mortality rate for individuals afflicted with LUAD remains elevated, and attaining an accurate prognosis is c...

    Authors: Zhe Wang, Jinyou Li, LongFei Wang, Yaowei Liu, Wei Wang, JiaYao Chen, HuiJun Liang, Y. Q. Chen and ShengLong Zhu
    Citation: Cellular & Molecular Biology Letters 2024 29:17
  3. Protein synthesis via translation is a central process involving several essential proteins called translation factors. Although traditionally described as cellular “housekeepers,” multiple studies have now su...

    Authors: Saket Awadhesbhai Patel, Md. Khurshidul Hassan and Manjusha Dixit
    Citation: Cellular & Molecular Biology Letters 2024 29:6
  4. The abnormality of chromosomal karyotype is one factor causing poor prognosis of lymphoma. In the analysis of abnormal karyotype of lymphoma patients, three smallest overlap regions were found, in which MYCT1 ...

    Authors: Ying Liang, Xin Wei, Peng-Jie Yue, He-Cheng Zhang, Zhen-Ning Li, Xiao-Xue Wang, Yuan-Yuan Sun and Wei-Neng Fu
    Citation: Cellular & Molecular Biology Letters 2024 29:5
  5. This study aims to explore the emerging trends, dynamic development, and research hotspots of clustered regularly interspaced short palindromic repeats (CRISPR) technology associated with extracellular vesicle...

    Authors: Jianjing Lin, Shicheng Jia, Zilu Jiao, Jiayou Chen, Wei Li, Fuyang Cao and Xintao Zhang
    Citation: Cellular & Molecular Biology Letters 2023 28:99
  6. PSA is a type of proto-oncogene that is specifically and highly expressed in embryonic and prostate cancer cells, but not expressed in normal prostate tissue cells. The specific expression of prostate-specific an...

    Authors: Yi Yang, Hongbing Mei, Xiaohong Han, Xintao Zhang, Jianli Cheng, Zhongfu Zhang, Han Wang and Haixia Xu
    Citation: Cellular & Molecular Biology Letters 2023 28:96
  7. Cancer remains a significant global health challenge, necessitating the exploration of novel and more precise therapeutic options beyond conventional treatments. In this regard, clustered regularly interspaced...

    Authors: Mingxia Wang, Menghui Chen, Xia Wu, Xinbo Huang and Bo Yu
    Citation: Cellular & Molecular Biology Letters 2023 28:73
  8. In recent years, N6-methyladenosine (m6A) methylation modification of mRNA has been studied extensively. It has been reported that m6A determines mRNA fate and participates in many cellular functions and reaction...

    Authors: Huan Li, Jun Zhao, Hao Deng, YuCheng Zhong, Mian Chen, LinSheng Chi, GuoQun Luo, Cong Cao, Cong Yu, Honghai Liu and Xinzong Zhang
    Citation: Cellular & Molecular Biology Letters 2023 28:72
  9. Chronic apical periodontitis is a prevalent oral disease characterized by bone loss, and its underlying mechanisms remain unclear. This study aimed to investigate the role and mechanism of the serine protease ...

    Authors: Tingting Jia, Fang Yuan, Jingqiao Tao, Gang Wang, Xianhua Zhang, Bin Zhang and Hongbo Li
    Citation: Cellular & Molecular Biology Letters 2023 28:70
  10. Improvements in treatment and chemotherapy have increased the survival rate of osteosarcoma, but overall efficacy remains low, highlighting the need for new gene therapy methods. Clustered regularly interspace...

    Authors: Yawei Hu, Hao Zhang, Zengfeng Guo, Jianhua Zhou, Wang Zhang, Ming Gong and Jiawen Wu
    Citation: Cellular & Molecular Biology Letters 2023 28:52
  11. The plasmid vector platform is the most commonly used vector for the expression of the versatile CRISPR-Cas technique and the promoter is a crucial element for the expression vector, thus profiling the impact ...

    Authors: Jinhe Li, Qinchun Liang, HuaPing Zhou, Ming Zhou and Hongxin Huang
    Citation: Cellular & Molecular Biology Letters 2023 28:41

    The Correction to this article has been published in Cellular & Molecular Biology Letters 2023 28:82

Submission Guidelines

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Before submitting your manuscript, please ensure you have read our submission guidelines. Articles for this Collection should be submitted via the submission system. During the submission process you will be asked whether you are submitting to a Collection, please select "Gene regulation tools for treating genetic diseases and cancers based on CRISPR-related technologies" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests.