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The Global Impact of Antibiotic Resistance on Emergency Surgery and Patient Safety

Cross-journal Special Issue

Antibiotic Resistance

Submission Status: Open   |   Submission Deadline: 31 October 2024

Guest Editor: Massimo Sartelli, MD, Global Alliance for Infections in Surgery & Macerata Hospital, Italy.

The threat of antibiotic resistance, otherwise known as antimicrobial resistance (AMR), represents arguably the greatest patient safety challenge of our time. It has been widely reported that the world is on the cusp of a “post-antibiotic era,” with the growth in multidrug-resistant bacteria raising the prospect that modern medicine will be increasingly unable to treat what are currently considered routine infections.

AMR occurs as bacteria, viruses, fungi, and parasites develop antimicrobial defence mechanisms that reduce treatment efficacy and increase the risk of treatment failure, disease progression, severe illness, or death. However, misuse and overuse of antimicrobial agents, combined with ineffective infection prevention and control practices, are recognized as major drivers of the increasing prevalence of AMR

Surgeons in their clinical practice are at the forefront of preventing and managing infections. However, among surgeons, appropriate measures of infection prevention and management are often disregarded. The lack of awareness of these measures has marginalized surgeons from this fight.

Surgeons are responsible for many of the processes of healthcare that impact the risk for surgical site infections and play an important role in their prevention. Surgeons are also at the forefront of managing patients with infections, who often need prompt source control and adequate antibiotic therapy being directly responsible for their outcomes. In this context, their leadership in the multidisciplinary efforts to improve the quality of the surgical patient is critical. If surgeons around the world participate in this global fight, they will be pivotal leaders in addressing this challenge. Otherwise, they will be contributors to the worst crisis that the world health is facing.

This special issue invites submissions that address the global burden of AMR and the principles of appropriate infection prevention and management across the surgical pathway, with particular interest in the emergency surgery setting where, considering the severity of the patients, respecting principles of infection prevention and management is of primary importance.

The following journals are accepting submissions to this special issue:

Patient Safety in Surgery - submission system here

World Journal of Emergency Surgery - submission system here

Manuscripts should be formatted according to the individual journals submission guidelines for authors and submitted to the collection via the online submission system.

Manuscripts will be peer-reviewed independently by the respective journal. Accepted articles will be published online on a continuous basis.

Pre-submission enquiries are welcome. If you have questions before submitting your manuscript, please contact us.


  1. Surgeons in their daily practice are at the forefront in preventing and managing infections. However, among surgeons, appropriate measures of infection prevention and management are often disregarded. The lack...

    Authors: Massimo Sartelli, Federico Coccolini, Luca Ansaloni, Walter L. Biffl, David P. Blake, Marja A. Boermeester, Raul Coimbra, Heather L. Evans, Paula Ferrada, George Gkiokas, Marc G. Jeschke, Timothy Hardcastle, Chandler Hinson, Francesco M. Labricciosa, Sanjay Marwah, Antonio C. Marttos…
    Citation: World Journal of Emergency Surgery 2023 18:56
  2. The objectives of the study were to investigate the organizational characteristics of acute care facilities worldwide in preventing and managing infections in surgery; assess participants’ perception regarding...

    Authors: Massimo Sartelli, Francesco M. Labricciosa, Federico Coccolini, Raul Coimbra, Fikri M. Abu-Zidan, Luca Ansaloni, Majdi N. Al-Hasan, Shamshul Ansari, Philip S. Barie, Miguel Angel Caínzos, Marco Ceresoli, Massimo Chiarugi, Jeffrey A. Claridge, Enrico Cicuttin, Evan Patchen Dellinger, Donald E. Fry…
    Citation: World Journal of Emergency Surgery 2022 17:17
  3. To describe our experience with outpatient transperineal biopsy (TPB) without antibiotics compared to transrectal biopsy (TRB) with antibiotics and bowel preparation. The literature elicits comparable cancer d...

    Authors: Majdee Islam, Rodrigo Donalisio Da Silva, Alan Quach, Diedra Gustafson, Leticia Nogueira, Nathan Clark and Fernando J. Kim
    Citation: Patient Safety in Surgery 2021 15:28
  4. Appropriate measures of infection prevention and management are integral to optimal clinical practice and standards of care. Among surgeons, these measures are often over-looked. However, surgeons are at the f...

    Authors: Massimo Sartelli, Federico Coccolini, Fikri M. Abu-Zidan, Luca Ansaloni, Stefano Bartoli, Walter Biffl, Felice Borghi, Elie Chouillard, Yunfeng Cui, Rafael De Oliveira Nascimento, Belinda De Simone, Salomone Di Saverio, Therese Duane, Christian Eckmann, Hani O. Eid, Carlos Augusto Gomes…
    Citation: World Journal of Emergency Surgery 2020 15:28
  5. Despite evidence supporting the effectiveness of best practices in infection prevention and management, many healthcare workers fail to implement them and evidence-based practices tend to be underused in routi...

    Authors: Massimo Sartelli, Leonardo Pagani, Stefania Iannazzo, Maria Luisa Moro, Pierluigi Viale, Angelo Pan, Luca Ansaloni, Federico Coccolini, Marcello Mario D’Errico, Iris Agreiter, Giorgio Amadio Nespola, Francesco Barchiesi, Valeria Benigni, Raffaella Binazzi, Stefano Cappanera, Alessandro Chiodera…
    Citation: World Journal of Emergency Surgery 2020 15:13
  6. Surgical Site Infections (SSI) are the most reported health acquired infection and common surgical complication in both developed and developing countries. In developing countries such as Rwanda, there is a pa...

    Authors: Marie Josée Mukagendaneza, Emmanuel Munyaneza, Esperance Muhawenayo, Dancilla Nyirasebura, Egide Abahuje, John Nyirigira, Jean De Dieu Harelimana, Thierry Zawadi Muvunyi, Florence Masaisa, Jean Claude Byiringiro, Théobald Hategekimana and Claude Mambo Muvunyi
    Citation: Patient Safety in Surgery 2019 13:10