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Fluid management

Edited by Hiroshi Morisaki

A number of issues regarding fluid therapy in critically ill patients have been debated for the last several decades. In this review series, published in Journal of Intensive Care, the principal and practical matters underlying fluid therapy are highlighted to allow the intensivists around the world to better understand and manage such primary and consistent intervention as fluid therapy in critically ill patients. The classic Starling’s principle, a 120-year-old model of the microvascular barrier, has recently been modified by such new discoveries as the endothelial glycocalyx and context-sensitive fluid shift.

This series of articles has not been sponsored. All articles have undergone the journal’s standard peer review process overseen by the Series Editor, with the final decisions made by the Editor-in-Chief. The Series Editor and Editor-in-Chief declare no competing interests in association with the series.

  1. Review

    Glycocalyx and its involvement in clinical pathophysiologies

    Vascular hyperpermeability is a frequent intractable feature involved in a wide range of diseases in the intensive care unit. The glycocalyx (GCX) seemingly plays a key role to control vascular permeability. T...

    Akira Ushiyama, Hanae Kataoka and Takehiko Iijima

    Journal of Intensive Care 2016 4:59

    Published on: 8 September 2016

  2. Review

    Fluid therapy in the perioperative setting—a clinical review

    Perioperative hypovolemia and fluid overload have effects on both complications following surgery and on patient survival. Therefore, the administration of intravenous fluids before, during, and after surgery ...

    Anders Winther Voldby and Birgitte Brandstrup

    Journal of Intensive Care 2016 4:27

    Published on: 16 April 2016

  3. Review

    Context-sensitive fluid therapy in critical illness

    Microcirculatory alterations are frequently observed in critically ill patients undergoing major surgery and those who suffer from trauma or sepsis. Despite the need for adequate fluid administration to restor...

    Tsuneo Tatara

    Journal of Intensive Care 2016 4:20

    Published on: 15 March 2016

  4. Review

    Pros and cons of tetrastarch solution for critically ill patients

    Proper fluid management is crucial for the management of critically ill patients. However, there is a continuing debate about the choice of the fluid, i.e., crystalloid vs. colloid. Colloid solution is theoret...

    Daisuke Toyoda, Shigeo Shinoda and Yoshifumi Kotake

    Journal of Intensive Care 2014 2:23

    Published on: 25 March 2014