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Extracellular Vesicles for Drug Delivery in Cancer Treatment

Guest Editors:
Wei-Qun Ding: The University of Oklahoma Health Sciences Center, USA
Chunxia Su: Tongji University, China

Biological Procedures Online is calling for submissions to our new Collection on "Extracellular Vesicles for Drug Delivery in Cancer Treatment". This Collection supports and amplifies research related to SDG 3, Good Health and Well-Being.

Image credit: Dr_Microbe /

About the collection

Extracellular vesicles (EVs) are lipid bilayer-enclosed, cell-derived nanoparticles, which include several subgroups such as exosomes, microvesicles, and apoptotic bodies. EVs have been shown to play a pleiotropic role in various physiological processes and pathological conditions via intercellular communication. In addition, as endogenously derived nanoparticles, certain types of EVs, especially those from mesenchymal stem cells or cancer cells, are favored carriers to deliver therapeutics because of their low immunogenicity and high capacity of homing toward cancer cells. Increasing studies demonstrate that EVs are stable membrane vesicles under different pH values, temperatures, or freeze-thaw cycles, and these properties support their potential compliance with good manufacturing practice (GMP) in clinical use. Thus, EVs have quickly garnered considerable attention as promising vehicles for drug delivery.

Diverse techniques have been employed to encapsulate cancer therapeutics by EVs to develop effective tumor-targeting vehicles, and ongoing clinical trials are testing the safety and efficacy of EV-encapsulated therapeutics. This Collection focuses on the use of EVs for cancer drug delivery, including but not limiting to the choice of EV sources, the drug encapsulation techniques, and the assessment of delivery efficiency and efficacy, etc.

  1. Extracellular vesicles (EVs) are nanoscale vesicles derived from cells that mediate intercellular communication by transporting bioactive molecules. They play significant roles in various physiological and pat...

    Authors: Li Wang, Xin Yu, Juan Zhou and Chunxia Su
    Citation: Biological Procedures Online 2023 25:28
  2. Exosomes, a special subtype of extracellular vesicles derived from human cells, serve as vital mediators of intercellular communication by transporting diverse bioactive cargos, including proteins and enzymes....

    Authors: Christopher Olson, Pengyang Zhang, Joy Ku, Renceh Flojo, Darin Boyes and Biao Lu
    Citation: Biological Procedures Online 2023 25:25
  3. In view of the limited data on radiotherapy (RT) combined with immunotherapy in patients with extensive-stage small cell lung cancer (ES-SCLC), this study aimed to identify the immune activation effect on diff...

    Authors: Min Wu, Shihao Wu, Yuetong Chen, Liangchao Sun and Jundong Zhou
    Citation: Biological Procedures Online 2023 25:24

Submission Guidelines

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This Collection welcomes submission of original Research Articles and Reviews. 

Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Extracellular Vesicles for Drug Delivery in Cancer Treatment" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests.