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Ensembl update 2010

This thematic series of methods papers describes the construction, content and use of Ensembl's resources. Ensembl is a joint project of the European Bioinformatics Institute (a part of the European Molecular Biology Laboratory) and the Wellcome Trust Sanger Institute. Ensembl enables genomic science by providing high quality, integrated annotation on vertebrate genomes within a consistent and accessible infrastructure. Components of the Ensembl project include the genome browser at http://www.ensembl.org, the Ensembl gene sets, the Ensembl API software and other data resources.

  1. Content type: Correspondence

    The number of databases in molecular biological fields has rapidly increased to provide a large-scale resource. Though valuable information is available, data can be difficult to access, compare and integrate ...

    Authors: Giulietta M Spudich and Xosé M Fernández-Suárez

    Citation: BMC Genomics 2010 11:295

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  2. Content type: Database

    The maturing field of genomics is rapidly increasing the number of sequenced genomes and producing more information from those previously sequenced. Much of this additional information is variation data derive...

    Authors: Yuan Chen, Fiona Cunningham, Daniel Rios, William M McLaren, James Smith, Bethan Pritchard, Giulietta M Spudich, Simon Brent, Eugene Kulesha, Pablo Marin-Garcia, Damian Smedley, Ewan Birney and Paul Flicek

    Citation: BMC Genomics 2010 11:293

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  3. Content type: Software

    Advances in sequencing and genotyping technologies are leading to the widespread availability of multi-species variation data, dense genotype data and large-scale resequencing projects. The 1000 Genomes Projec...

    Authors: Daniel Rios, William M McLaren, Yuan Chen, Ewan Birney, Arne Stabenau, Paul Flicek and Fiona Cunningham

    Citation: BMC Bioinformatics 2010 11:238

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  4. Content type: Methodology article

    The Ensembl project produces updates to its comparative genomics resources with each of its several releases per year. During each release cycle approximately two weeks are allocated to generate all the genomi...

    Authors: Jessica Severin, Kathryn Beal, Albert J Vilella, Stephen Fitzgerald, Michael Schuster, Leo Gordon, Abel Ureta-Vidal, Paul Flicek and Javier Herrero

    Citation: BMC Bioinformatics 2010 11:240

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  5. Content type: Methodology article

    Gene expression arrays are valuable and widely used tools for biomedical research. Today's commercial arrays attempt to measure the expression level of all of the genes in the genome. Effectively translating t...

    Authors: Benoît Ballester, Nathan Johnson, Glenn Proctor and Paul Flicek

    Citation: BMC Genomics 2010 11:294

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  6. Content type: Correspondence

    The Ensembl web site has provided access to genomic information for almost 10 years. During this time the amount of data available through Ensembl has grown dramatically. At the same time, the World Wide Web i...

    Authors: Anne Parker, Eugene Bragin, Simon Brent, Bethan Pritchard, James A Smith and Stephen Trevanion

    Citation: BMC Bioinformatics 2010 11:239

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