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Extracellular vesicles

Edited by:
Ajay Singh, PhD, Mitchell Cancer Institute, University of South Alabama, United States of America

Submission Status: Open   |   Submission Deadline: 30 June 2024


Journal of Ovarian Research is calling for submissions to our collection on Extracellular vesicles. Extracellular vesicles (EVs) are a heterogeneous group of cell-derived vesicles mediating the intercellular crosstalk. In this collection, we welcome original research articles, review manuscripts, as well as short communications that highlight the role of EVs in ovarian biology and pathobiology, targeting of their biogenesis and functions for therapeutic gain, and their potential utility in biomarker development and as drug delivery systems.

Image credit: © Meletios Verras / Getty Images / iStock

About the collection

Journal of Ovarian Research is calling for submissions to our collection on Extracellular vesicles. Extracellular vesicles (EVs) are a heterogeneous group of cell-derived vesicles mediating the intercellular crosstalk. 

These vesicles carry the bioactive cargo from the donor cells, such as nucleic acids, proteins, lipids, and metabolites, and transfer it to the recipient cells both locally and remotely, causing a change in their behavior. The release and composition of EVs is altered under pathological conditions, which can have a significant impact on the pathobiological processes. EVs can help in the adaptation of cells to the harsh environmental conditions as well as facilitate the remodeling of stroma. Researchers are unveiling the functions of EVs at a rapid pace in reproductive process, stem cell biology, and malignancy. A role of EVs in immune modulation and therapeutic resistance is also being investigated. Further, being a natural carrier of biomolecules and their easy modifiability to enhance cell-specific targeting and cellular uptake, EVs represent a useful candidate for the development of efficient drug delivery systems. EVs are also a useful resource for biomarker development to assist in disease diagnosis, predicting the disease status, and monitoring of the therapeutic responses.

In this collection, we welcome original research articles, review manuscripts, as well as short communications that highlight the role of EVs in ovarian biology and pathobiology, targeting of their biogenesis and functions for therapeutic gain, and their potential utility in biomarker development and as drug delivery systems.

  1. Ovarian cancer accounts for more deaths than any other female reproductive tract cancer. The major reasons for the high mortality rates include delayed diagnoses and drug resistance. Hence, improved diagnostic...

    Authors: Dhaval Bhavsar, Rajeswari Raguraman, Dongin Kim, Xiaoyu Ren, Anupama Munshi, Kathleen Moore, Vassilios Sikavitsas and Rajagopal Ramesh
    Citation: Journal of Ovarian Research 2024 17:113
  2. Chemotherapy exposure has become a main cause of premature ovarian insufficiency (POI). This study aimed to evaluate the role and molecular mechanism of human umbilical cord mesenchymal stem cell-derived exoso...

    Authors: Yuan Zhou, Jinfa Huang, Lingling Zeng, Qian Yang, Fangjuan Bai, Qiqing Mai and Kaixian Deng
    Citation: Journal of Ovarian Research 2024 17:80
  3. It is well described that circulating progesterone (P4) plays a key role in several reproductive events such as oocyte maturation. However, during diestrus, when circulating P4 is at the highest concentrations...

    Authors: Paola Maria da Silva Rosa, Alessandra Bridi, Giuliana de Ávila Ferronato, Cibele Maria Prado, Natália Marins Bastos, Juliano Rodrigues Sangalli, Flávio Vieira Meirelles, Felipe Perecin and Juliano Coelho da Silveira
    Citation: Journal of Ovarian Research 2024 17:65
  4. Investigating the utility of serum exosomal markers CA125, HE4, and C5a, both individually and in combination, for distinguishing between benign and malignant ovarian tumors.

    Authors: Huihui Shi, Liya Liu, Xueli Deng, Xiaoyu Xing, Yan Zhang, Yemeli Djouda Rebecca and Liping Han
    Citation: Journal of Ovarian Research 2024 17:4
  5. The epithelial-mesenchymal transition (EMT) promotes cell signaling and morphology alterations, contributing to cancer progression. Exosomes, extracellular vesicles containing proteins involved in cell-cell co...

    Authors: Germano Aguiar Ferreira, Carolina Hassibe Thomé, Clarice Izumi, Mariana Lopes Grassi, Guilherme Pauperio Lanfredi, Marcus Smolka, Vitor Marcel Faça and Francisco José Candido dos Reis
    Citation: Journal of Ovarian Research 2023 16:232

Submission Guidelines

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This Collection welcomes submission of original research articles, review manuscripts, as well as short communications.

Before submitting your manuscript, please ensure you have read our submission guidelines. Articles for this collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a collection, please select "Extracellular vesicles" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the collection as they are published.

The Editor has no competing interests with the submissions which he will handle through the peer review process. The peer review of any submissions for which the Editor have competing interests is handled by another Editorial Board Member who has no competing interests.