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Coronavirus research highlights

A novel coronavirus, 2019-nCoV, has been identified as the cause of an outbreak of respiratory illness that originated in Wuhan, China, and which has spread to several other countries around the world.  Recent content from BMC and SpringerOpen journals relevant to coronavirus research, as well as additional commentary on this topic, is included below. 

BMC, as part of Springer Nature, encourages early sharing of research submitted to all our journals through preprints, and our In Review preprint service is available for many journals. We strongly urge authors submitting articles related to this emergency to BMC journals to share underlying interim and final research datasets relating to the outbreak as rapidly and widely as possible, including with public health and research communities and the WHO.

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  1. Hydroxychloroquine (HCQ) is the standard of care in the treatment of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and other inflammatory rheumatic diseases and potentially for the treatment i...

    Authors: Henrik Carlsson, Karin Hjorton, Sandy Abujrais, Lars Rönnblom, Torbjörn Åkerfeldt and Kim Kultima
    Citation: Arthritis Research & Therapy 2020 22:125
    Content type: Research article Published on:

  2. A cluster of pneumonia cases were reported by Wuhan Municipal Health Commission, China in December 2019. A novel coronavirus was eventually identified, and became the COVID-19 epidemic that affected public hea...

    Authors: Xi Liu, Wen-Tao Luo, Ying Li, Chun-Na Li, Zhong-Si Hong, Hui-Li Chen, Fei Xiao and Jin-Yu Xia
    Citation: Infectious Diseases of Poverty 2020 9:58
    Content type: Research Article Published on:

  3. The novel SARS-CoV-2 coronavirus pandemic has emerged as a truly formidable threat to humankind’s existence. In the wake of the massively volatile global situation created by COVID-19, it is vital to recognize...

    Authors: Akaninyene Otu, Carlo Handy Charles and Sanni Yaya
    Citation: International Journal of Mental Health Systems 2020 14:38
    Content type: Commentary Published on:

  4. The novel coronavirus disease 2019 (COVID-19) has grown to be a global public health emergency since patients were first detected in Wuhan, China. Thus far, no specific drugs or vaccines are available to cure ...

    Authors: Yingxin Zhang, Jie Ding, Shaoda Ren, Weihua Wang, Yapei Yang, Shuangjing Li, Min Meng, Tiejun Wu, Daliang Liu, Suochen Tian, Hui Tian, Shuangfeng Chen and Changhui Zhou
    Citation: Stem Cell Research & Therapy 2020 11:207
    Content type: Short report Published on:

  5. Northeastern Nigeria has over the decade suffered from the Boko Haram insurgency and is still in the process of recovery from the complex humanitarian crisis that has displaced and subjected millions of vulner...

    Authors: Salman Jidda Tijjani and Le Ma
    Citation: International Journal for Equity in Health 2020 19:77
    Content type: Commentary Published on:

  6. Reported COVID-19 deaths in Germany are relatively low as compared to many European countries. Among the several explanations proposed, an early and large testing of the population was put forward. Most curren...

    Authors: Jean Bousquet, Josep M. Anto, Guido Iaccarino, Wienczyslawa Czarlewski, Tari Haahtela, Aram Anto, Cezmi A. Akdis, Hubert Blain, G. Walter Canonica, Victoria Cardona, Alvaro A. Cruz, Maddalena Illario, Juan Carlos Ivancevich, Marek Jutel, Ludger Klimek, Piotr Kuna…
    Citation: Clinical and Translational Allergy 2020 10:16
    Content type: Review Published on:

    The Correction to this article has been published in Clinical and Translational Allergy 2020 10:44

  7. Coronavirus disease 2019 (COVID-19), caused by a novel corinavirus (later named SARS-CoV-2 virus), was fistly reported in Wuhan, Hubei Province, China towards the end of 2019. Large-scale spread within China a...

    Authors: Yeming Wang, Fei Zhou, Dingyu Zhang, Jianping Zhao, Ronghui Du, Yi Hu, Zhenshun Cheng, Ling Gao, Yang Jin, Guangwei Luo, Shouzhi Fu, Qiaofa Lu, Guanhua Du, Ke Wang, Yang Lu, Guohui Fan…
    Citation: Trials 2020 21:422
    Content type: Study protocol Published on:

  8. Acute lung injury (ALI), an increasingly devastating human disorder, is characterized by a multitude of lung changes arising from a wide variety of lung injuries. Viral infection is the main cause of morbidity...

    Authors: Jiang Du, Han Li, Jie Lian, Xinxing Zhu, Liang Qiao and Juntang Lin
    Citation: Stem Cell Research & Therapy 2020 11:192
    Content type: Review Published on:

  9. A cluster of patients with coronavirus disease 2019 (COVID-19) pneumonia were discharged from hospitals in Wuhan, China. We aimed to determine the cumulative percentage of complete radiological resolution at e...

    Authors: Dehan Liu, Wanshu Zhang, Feng Pan, Lin Li, Lian Yang, Dandan Zheng, Jiazheng Wang and Bo Liang
    Citation: Respiratory Research 2020 21:125
    Content type: Research Published on:

  10. Patients with critical illness due to infection with the 2019 coronavirus disease (COVID-19) show rapid disease progression to acute respiratory failure. The study aimed to screen the most useful predictive fa...

    Authors: Jingyuan Liu, Yao Liu, Pan Xiang, Lin Pu, Haofeng Xiong, Chuansheng Li, Ming Zhang, Jianbo Tan, Yanli Xu, Rui Song, Meihua Song, Lin Wang, Wei Zhang, Bing Han, Li Yang, Xiaojing Wang…
    Citation: Journal of Translational Medicine 2020 18:206
    Content type: Research Published on:

  11. Since its introduction in modern medicine, naturalistic observations emerged about possible uses of lithium treatment for conditions different from recurring affective disorders, for which it is still a first-...

    Authors: Andrea Murru, Mirko Manchia, Tomas Hajek, René E. Nielsen, Janusz K. Rybakowski, Gabriele Sani, Thomas G. Schulze, Leonardo Tondo and Michael Bauer
    Citation: International Journal of Bipolar Disorders 2020 8:21
    Content type: Review Published on:

  12. The need for life-saving interventions such as mechanical ventilation may threaten to outstrip resources during the Covid-19 pandemic. Allocation of these resources to those most likely to benefit can be suppo...

    Authors: David M. Kent, Jessica K. Paulus, Richard R. Sharp and Negin Hajizadeh
    Citation: Diagnostic and Prognostic Research 2020 4:11
    Content type: Commentary Published on:

  13. The COVID-19 pandemic has become the leading societal concern. The pandemic has shown that the public health concern is not only a medical problem, but also affects society as a whole; so, it has also become t...

    Authors: Negar Moradian, Hans D. Ochs, Constantine Sedikies, Michael R. Hamblin, Carlos A. Camargo Jr., J. Alfredo Martinez, Jacob D. Biamonte, Mohammad Abdollahi, Pedro J. Torres, Juan J. Nieto, Shuji Ogino, John F. Seymour, Ajith Abraham, Valentina Cauda, Sudhir Gupta, Seeram Ramakrishna…
    Citation: Journal of Translational Medicine 2020 18:205
    Content type: Review Published on:

  15. The Corona Virus Disease 2019 (COVID-19) is an acute respiratory infectious disease. At present, COVID-19 has no specific therapeutic drugs, and the main clinical treatment is symptomatic treatment and control...

    Authors: Jianxia Wen, Ruilin Wang, Honghong Liu, Yuling Tong, Shizhang Wei, Xuelin Zhou, Haotian Li, Manyi Jing, Min Wang and Yanling Zhao
    Citation: Chinese Medicine 2020 15:48
    Content type: Review Published on:

  16. In late 2019, a novel coronavirus (SARS-CoV-2) emerged in Wuhan, capital city of Hubei province in China. Cases of SARS-CoV-2 infection quickly grew by several thousand per day. Less than 100 days later, the W...

    Authors: Christopher J. Rogers, Robert J. Harman, Bruce A. Bunnell, Martin A. Schreiber, Charlie Xiang, Fu-Sheng Wang, Antonio F. Santidrian and Boris R. Minev
    Citation: Journal of Translational Medicine 2020 18:203
    Content type: Review Published on:

  17. Medical staff caring for COVID-19 patients face mental stress, physical exhaustion, separation from families, stigma, and the pain of losing patients and colleagues. Many of them have acquired SARS-CoV-2 and s...

    Authors: Matthew F. Chersich, Glenda Gray, Lee Fairlie, Quentin Eichbaum, Susannah Mayhew, Brian Allwood, Rene English, Fiona Scorgie, Stanley Luchters, Greg Simpson, Marjan Mosalman Haghighi, Minh Duc Pham and Helen Rees
    Citation: Globalization and Health 2020 16:46
    Content type: Review Published on:

  18. The rapid spread of the corona virus pandemic is an existential problem for many people in numerous countries. So far, there is no effective vaccine protection or proven therapy available against the SARS-CoV-...

    Authors: Johannes C. Fischer, Kurt Zänker, Martijn van Griensven, Marion Schneider, Detlef Kindgen-Milles, Wolfram Trudo Knoefel, Artur Lichtenberg, Balint Tamaskovics, Freddy Joel Djiepmo-Njanang, Wilfried Budach, Stefanie Corradini, Ute Ganswindt, Dieter Häussinger, Torsten Feldt, Hubert Schelzig, Hans Bojar…
    Citation: European Journal of Medical Research 2020 25:16
    Content type: Review Published on:

    The Correction to this article has been published in European Journal of Medical Research 2020 25:53

  19. We present the rationale for a novel allo-priming approach to serve the elderly as a universal anti-virus vaccine, as well serving to remodel the aging immune system in order to reverse immunosenescence and in...

    Authors: Michael Har-Noy and Reuven Or
    Citation: Journal of Translational Medicine 2020 18:196
    Content type: Review Published on:

  20. The recent pandemic caused by the 2019 outbreak of novel coronavirus (2019-nCoV or COVID-19) has affected more than 3.0 million people resulting ~ 212,000 deaths across 215 countries/territories as on 28th Apr...

    Authors: Sachin S. Gunthe and Satya S. Patra
    Citation: Globalization and Health 2020 16:45
    Content type: Commentary Published on:

  21. The coronavirus disease 2019 (COVID-19) is profoundly affecting life around the globe. Isolation, contact restrictions and economic shutdown impose a complete change to the psychosocial environment in affected...

    Authors: Jörg M. Fegert, Benedetto Vitiello, Paul L. Plener and Vera Clemens
    Citation: Child and Adolescent Psychiatry and Mental Health 2020 14:20
    Content type: Review Published on:

  22. The triglyceride and glucose index (TyG) has been proposed as a marker of insulin resistance. This study aims to evaluate the association of the TyG index with the severity and mortality of coronavirus disease...

    Authors: Huihui Ren, Yan Yang, Fen Wang, Yongli Yan, Xiaoli Shi, Kun Dong, Xuefeng Yu and Shujun Zhang
    Citation: Cardiovascular Diabetology 2020 19:58
    Content type: Original investigation Published on:

  23. COVID-19 is a rapidly spreading virus infection that has quickly caused extensive burden to individual, families, countries, and the globe. No intervention has yet been proven effective for the treatment of CO...

    Authors: Sophie Juul, Niklas Nielsen, Peter Bentzer, Areti Angeliki Veroniki, Lehana Thabane, Adam Linder, Sarah Klingenberg, Christian Gluud and Janus Christian Jakobsen
    Citation: Systematic Reviews 2020 9:108
    Content type: Protocol Published on:

  24. The coronavirus disease 2019 (COVID-2019) pandemic struck Latin America in late February and is now beginning to spread across the rural indigenous communities in the region, home to 42 million people. Eighty ...

    Authors: Sergio Meneses-Navarro, María Graciela Freyermuth-Enciso, Blanca Estela Pelcastre-Villafuerte, Roberto Campos-Navarro, David Mariano Meléndez-Navarro and Liliana Gómez-Flores-Ramos
    Citation: International Journal for Equity in Health 2020 19:63
    Content type: Commentary Published on:

  25. On February 19th 2020, the Iranian Ministry of Health and Medical Education (MoHME) has announced the first 2 cases of SARS-CoV-2, a novel emerging coronavirus which causes an infection termed as COVID-19, in Qom...

    Authors: Masoud Behzadifar, Mahboubeh Khaton Ghanbari, Ahad Bakhtiari, Meysam Behzadifar and Nicola Luigi Bragazzi
    Citation: International Journal for Equity in Health 2020 19:61
    Content type: Commentary Published on:

  26. The impact of COVID-19 across health services, including treatment services for people who use drugs, is emerging but likely to have a high impact. Treatment services for people who use drugs provide essential...

    Authors: Adrian Dunlop, Buddhima Lokuge, Debbie Masters, Marcia Sequeira, Peter Saul, Grace Dunlop, John Ryan, Michelle Hall, Nadine Ezard, Paul Haber, Nicholas Lintzeris and Lisa Maher
    Citation: Harm Reduction Journal 2020 17:26
    Content type: Opinion Published on:

  28. A new human coronavirus named SARS-CoV-2 was identified in several cases of acute respiratory syndrome in Wuhan, China in December 2019. On March 11 2020, WHO declared the SARS-CoV-2 infection to be a pandemic...

    Authors: Luigi Buonaguro, Maria Tagliamonte, Maria Lina Tornesello and Franco M. Buonaguro
    Citation: Journal of Translational Medicine 2020 18:185
    Content type: Commentary Published on:

  29. The outbreak of 2019 novel coronavirus disease (COVID-19) worldwide is becoming rapidly a major concern. The number of severe cases has increased dramatically worldwide, while specific treatment options are sc...

    Authors: Shan Liu, Danyi Peng, Huijun Qiu, Ke Yang, Zhou Fu and Lin Zou
    Citation: Stem Cell Research & Therapy 2020 11:169
    Content type: Commentary Published on:

  30. The novel coronavirus (2019-nCoV) is an emerging causative agent that was first described in late December 2019 and causes a severe respiratory infection in humans. Notably, many of affected patients of COVID-...

    Authors: Peiwei Chai, Jie Yu, Shengfang Ge, Renbing Jia and Xianqun Fan
    Citation: Journal of Hematology & Oncology 2020 13:43
    Content type: Letter to the Editor Published on:

  32. The world is currently dominated by the Corona Virus Disease 2019 (COVID-19) pandemic. Besides the obvious concerns about limitation of virus spread and providing the best possible care to infected patients, a...

    Authors: Antoinette MaassenVanDenBrink, Tessa de Vries and A. H. Jan Danser
    Citation: The Journal of Headache and Pain 2020 21:38
    Content type: Commentary Published on:

  33. The novel coronavirus disease (COVID-19) outbreak was first declared in China in December 2019, and WHO declared the pandemic on 11 March 2020. A fast-rising number of confirmed cases has been observed in all ...

    Authors: Kun Tang, Junjian Gaoshan, Babatunde Ahonsi, Moazzam Ali, Mercedes Bonet, Nathalie Broutet, Edna Kara, Caron Kim, Anna Thorson and Soe Soe Thwin
    Citation: Reproductive Health 2020 17:59
    Content type: Commentary Published on:

    The Correction to this article has been published in Reproductive Health 2020 17:76

  34. SARS-CoV-2 is a RNA coronavirus responsible for the pandemic of the Severe Acute Respiratory Syndrome (COVID-19). RNA viruses are characterized by a high mutation rate, up to a million times higher than that o...

    Authors: Maria Pachetti, Bruna Marini, Francesca Benedetti, Fabiola Giudici, Elisabetta Mauro, Paola Storici, Claudio Masciovecchio, Silvia Angeletti, Massimo Ciccozzi, Robert C. Gallo, Davide Zella and Rudy Ippodrino
    Citation: Journal of Translational Medicine 2020 18:179
    Content type: Research Published on:

  35. The novel coronavirus disease (COVID-19) outbreak started in December 2019 in Wuhan, China, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The CT image is used to assess the disease pr...

    Authors: Jing Gao, Jun-Qiang Liu, Heng-Jun Wen, Hua Liu, Wei-Dong Hu, Xia Han, Chuan-Xing Li and Xiao-Jun Wang
    Citation: Respiratory Research 2020 21:96
    Content type: Letter to the Editor Published on:

  36. On March 11th, 2020 the World Health Organization declared COVID-19 a global pandemic. The infection, transmitted by 2019 novel coronavirus (2019-nCov), was first discovered in December 2019, in Wuhan, Hubei P...

    Authors: Francesco Licciardi, Teresa Giani, Letizia Baldini, Ennio Giulio Favalli, Roberto Caporali and Rolando Cimaz
    Citation: Pediatric Rheumatology 2020 18:35
    Content type: Review Published on:

  37. The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China has been declared a public health emergency of international concern. The car...

    Authors: Lei Gao, Dan Jiang, Xue-song Wen, Xiao-cheng Cheng, Min Sun, Bin He, Lin-na You, Peng Lei, Xiao-wei Tan, Shu Qin, Guo-qiang Cai and Dong-ying Zhang
    Citation: Respiratory Research 2020 21:83
    Content type: Research Published on:

  38. A novel coronavirus was identified in December, 2019 in Wuhan, China, and traditional Chinese medicine (TCM) played an active role in combating the novel coronavirus pneumonia (NCP) caused by this fast-spreadi...

    Authors: Erdan Luo, Daiyan Zhang, Hua Luo, Bowen Liu, Keming Zhao, Yonghua Zhao, Ying Bian and Yitao Wang
    Citation: Chinese Medicine 2020 15:34
    Content type: Research Published on:

  41. A new type of coronavirus, novel coronavirus (COVID-19), is causing an increasing number of cases of pneumonia and was declared a Public Health Emergency of International Concern by the World Health Organizati...

    Authors: Yuxi Li, Xiaobo Liu, Liuxue Guo, Juan Li, Dongling Zhong, Yonggang Zhang, Mike Clarke and Rongjiang Jin
    Citation: Systematic Reviews 2020 9:75
    Content type: Protocol Published on:

  42. The outbreak of coronavirus disease 2019 (COVID-19) has caused more than 80 813 confirmed cases in all provinces of China, and 21 110 cases reported in 93 countries of six continents as of 7 March 2020 since m...

    Authors: Xu Qian, Ran Ren, Youfa Wang, Yan Guo, Jing Fang, Zhong-Dao Wu, Pei-Long Liu and Tie-Ru Han
    Citation: Infectious Diseases of Poverty 2020 9:34
    Content type: Commentary Published on:

  43. Since the first case of a coronavirus disease 2019 (COVID-19) infection pneumonia was detected in Wuhan, China, a series of confirmed cases of the COVID-19 were found in Southwest China. The aim of this study ...

    Authors: Xiaoming Li, Wenbing Zeng, Xiang Li, Haonan Chen, Linping Shi, Xinghui Li, Hongnian Xiang, Yang Cao, Hui Chen, Chen Liu and Jian Wang
    Citation: Journal of Translational Medicine 2020 18:154
    Content type: Research Published on:

  46. Coronavirus can cross the species barrier and infect humans with a severe respiratory syndrome. SARS-CoV-2 with potential origin of bat is still circulating in China. In this study, a prediction model is propo...

    Authors: Xiao-Li Qiang, Peng Xu, Gang Fang, Wen-Bin Liu and Zheng Kou
    Citation: Infectious Diseases of Poverty 2020 9:33
    Content type: Research Article Published on:

  48. The coronavirus disease (COVID-19) has been identified as the cause of an outbreak of respiratory illness in Wuhan, Hubei Province, China beginning in December 2019. As of 31 January 2020, this epidemic had sp...

    Authors: Sasmita Poudel Adhikari, Sha Meng, Yu-Ju Wu, Yu-Ping Mao, Rui-Xue Ye, Qing-Zhi Wang, Chang Sun, Sean Sylvia, Scott Rozelle, Hein Raat and Huan Zhou
    Citation: Infectious Diseases of Poverty 2020 9:29
    Content type: Scoping Review Published on:

  49. In December 2019, a new virus (initially called ‘Novel Coronavirus 2019-nCoV’ and later renamed to SARS-CoV-2) causing severe acute respiratory syndrome (coronavirus disease COVID-19) emerged in Wuhan, Hubei P...

    Authors: Maged N. Kamel Boulos and Estella M. Geraghty
    Citation: International Journal of Health Geographics 2020 19:8
    Content type: Editorial Published on:

  50. As reported by the World Health Organization, a novel coronavirus (2019-nCoV) was identified as the causative virus of Wuhan pneumonia of unknown etiology by Chinese authorities on 7 January, 2020. The virus w...

    Authors: Tian-Mu Chen, Jia Rui, Qiu-Peng Wang, Ze-Yu Zhao, Jing-An Cui and Ling Yin
    Citation: Infectious Diseases of Poverty 2020 9:24
    Content type: Research Article Published on: