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Coronavirus research highlights

A novel coronavirus, 2019-nCoV, has been identified as the cause of an outbreak of respiratory illness that originated in Wuhan, China, and which has spread to several other countries around the world.  Recent content from BMC and SpringerOpen journals relevant to coronavirus research, as well as additional commentary on this topic, is included below. 

BMC, as part of Springer Nature, encourages early sharing of research submitted to all our journals through preprints, and our In Review preprint service is available for many journals. We strongly urge authors submitting articles related to this emergency to BMC journals to share underlying interim and final research datasets relating to the outbreak as rapidly and widely as possible, including with public health and research communities and the WHO.

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  1. Type 2 Diabetes Mellitus (T2DM) is a well-known comorbidity to COVID-19 and coagulopathies are a common accompaniment to both T2DM and COVID-19. In addition, patients with COVID-19 are known to develop micro-c...

    Authors: Etheresia Pretorius, Chantelle Venter, Gert Jacobus Laubscher, Petrus Johannes Lourens, Janami Steenkamp and Douglas B. Kell
    Citation: Cardiovascular Diabetology 2020 19:193
  2. The COVID-19 pandemic led to the closure of the IDEA syringe services program medical student-run free clinic in Miami, Florida. In an effort to continue to serve the community of people who inject drugs and p...

    Authors: Marcus Castillo, Brianna Conte, Sam Hinkes, Megan Mathew, C. J. Na, Ainhoa Norindr, David P. Serota, David W. Forrest, Amar R. Deshpande, Tyler S. Bartholomew and Hansel E. Tookes
    Citation: Harm Reduction Journal 2020 17:88
  3. Investigating clinical characteristics of patients presenting with cerebrovascular events during the pandemic may provide valuable insight into further understanding the phenomenon of decreased stroke admissio...

    Authors: Carolin Hoyer, Lenja Weber, Vesile Sandikci, Anne Ebert, Michael Platten and Kristina Szabo
    Citation: Neurological Research and Practice 2020 2:47
  4. COVID-19, the illness caused by the SARS-CoV-2 virus, has reached pandemic proportions. Although the virus can cause disease in anyone, it is particularly dangerous for those with various “co-morbidities” such...

    Authors: A. Mark Clarfield and Alan Jotkowitz
    Citation: Israel Journal of Health Policy Research 2020 9:64
  5. Only one in four people with eating disorders seeks treatment, and of those who do seek treatment, 20% go on to experience a chronic course. Early intervention has been associated with better prognosis, with t...

    Authors: Emma Bryant, Jane Miskovic-Wheatley, Stephen Touyz, Ross D. Crosby, Eyza Koreshe, Li Cao and Sarah Maguire
    Citation: Journal of Eating Disorders 2020 8:60
  6. Prior to the COVID-19 pandemic, 44% of all reported injuries in U.S. households occurred in the home. Spending more time at home due to the pandemic may increase the number of home injuries.

    Authors: Andrea C. Gielen, Grace Bachman, Oluwakemi Badaki-Makun, Renee M. Johnson, Eileen McDonald, Elise Omaki, Keshia M. Pollack Porter, Leticia Ryan and Wendy Shields
    Citation: Injury Epidemiology 2020 7:63
  7. At present, “severe acute respiratory syndrome new coronavirus” (SARS-CoV-2) affects the whole world and has led to a pandemia with almost 2.000.000 infected patients in the mid of April 2020 (WHO). Thus, heal...

    Authors: Christian Urbanek, Jana Kötteritzsch, Wolfgang Zink and Armin J. Grau
    Citation: Neurological Research and Practice 2020 2:32
  8. Several recent studies suggest the possibility of a skin rash being a clinical presentation of coronavirus disease 2019 (COVID-19). The purpose of this case report is to bring attention to skin manifestations ...

    Authors: Alice Serafini, Peter Konstantin Kurotschka, Mariabeatrice Bertolani and Silvia Riccomi
    Citation: Journal of Medical Case Reports 2020 14:216
  9. On December 12, 2019 a new coronavirus (SARS-CoV-2) emerged in Wuhan, China, triggering a pandemic of severe acute respiratory syndrome in humans (COVID-19). Today, the scientific community is investing all th...

    Authors: Laura Di Renzo, Paola Gualtieri, Francesca Pivari, Laura Soldati, Alda Attinà, Claudia Leggeri, Giulia Cinelli, Maria Grazia Tarsitano, Giovanna Caparello, Elena Carrano, Giuseppe Merra, Alberto Maria Pujia, Roberta Danieli and Antonino De Lorenzo
    Citation: Journal of Translational Medicine 2020 18:415
  10. Previous studies on the impact of corona virus disease 2019 (COVID-19) on the mental health of the patients has been limited by the lack of relevant data. With the rapid and sustained growth of the publication...

    Authors: Jiyuan Shi, Ya Gao, Liang Zhao, Yuanyuan Li, Meili Yan, Ming Ming Niu, Yamin Chen, Ziwei Song, Ruixing Zhang, Lili Zhang and Jinhui Tian
    Citation: Systematic Reviews 2020 9:258
  11. Since the birth of Christ, in these 2019 years, the man on earth has never experienced a survival challenge from any acellular protist compared to SARS-CoV-2. No specific drugs yet been approved. The host immu...

    Authors: Kishalay Paria, Debarati Paul, Trinath Chowdhury, Smritikana Pyne, Ranadhir Chakraborty and Santi M. Mandal
    Citation: Translational Medicine Communications 2020 5:21
  12. The COVID-19 pandemic has created a sense of urgency in the research community in their bid to contribute to the evidence required for healthcare policy decisions. With such urgency, researchers experience met...

    Authors: Linda Biesty, Pauline Meskell, Claire Glenton, Hannah Delaney, Mike Smalle, Andrew Booth, Xin Hui S. Chan, Declan Devane and Catherine Houghton
    Citation: Systematic Reviews 2020 9:256
  13. Since the World Health Organization declared a global pandemic due to the novel coronavirus disease2019, there have been targeted efforts to establish management modalities. Hydroxychloroquine has been suggest...

    Authors: Ivorie Coleman, Gabriel Ruiz, Sumir Brahmbhatt and Lindsay Ackerman
    Citation: Journal of Medical Case Reports 2020 14:210
  14. - To describe the evolution of the SARS-CoV-2 salivary viral load of patients infected with Covid-19, performing 7 days of tri-daily mouthwashes with and without antivirals.

    Authors: Florence Carrouel, Stéphane Viennot, Martine Valette, Jean-Marie Cohen, Claude Dussart and Denis Bourgeois
    Citation: Trials 2020 21:906
  15. The SARS-CoV-2 RNA was detected positive again after discharged from hospital in some COVID-19 patients, with or without clinical symptoms such as fever or dry cough.

    Authors: Yongqing Tong, Anyu Bao, Hongbing Chen, Jingtao Huang, Zhihua Lv, Lina Feng, Yun Cheng, Youna Wang, Li Bai, Wenlong Rao, Hongyun Zheng, Zegang Wu, Bin Qiao, Zhijun Zhao, Huiming Wang and Yan Li
    Citation: Journal of Translational Medicine 2020 18:411
  16. Israel hosts nearly 70,000 migrant careworkers. Migrant careworkers work and live with populations extremely vulnerable to the novel Coronavirus, including the elderly and people with pre-existing physical con...

    Authors: Jordan Hannink Attal, Ido Lurie and Yehuda Neumark
    Citation: Israel Journal of Health Policy Research 2020 9:61
  17. Lockdown implemented to prevent the COVID-19 spread resulted in marked changes in the lifestyle. The objective of the current study was to assess the impact of lockdown measures on a cohort of eating disorder ...

    Authors: Paulo P. P. Machado, Ana Pinto-Bastos, Rita Ramos, Tânia F. Rodrigues, Elsa Louro, Sónia Gonçalves, Isabel Brandão and Ana Vaz
    Citation: Journal of Eating Disorders 2020 8:57
  18. COronaVIrus Disease 19 (COVID-19) is caused by the infection of the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2). Although the main clinical manifestations of COVID-19 are respiratory, many pat...

    Authors: S. Greco, A. Madè, C. Gaetano, Y. Devaux, C. Emanueli and F. Martelli
    Citation: Journal of Translational Medicine 2020 18:408
  19. The use of telemedicine in pediatric rheumatology has been historically low. The current COVID 19 global pandemic has forced a paradigm shift with many centers rapidly adopting virtual visits to conduct care r...

    Authors: Susan Shenoi, Kristen Hayward, Megan L. Curran, Elizabeth Kessler, Jay J. Mehta, Meredith P. Riebschleger and Helen E. Foster
    Citation: Pediatric Rheumatology 2020 18:85
  20. It has been recently hypothesized that infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to fibrotic sequelae in patients recovering from coronavirus disease 2019 (COVID-19). I...

    Authors: Paola Rogliani, Luigino Calzetta, Angelo Coppola, Ermanno Puxeddu, Gianluigi Sergiacomi, Dejanira D’Amato and Antonio Orlacchio
    Citation: Respiratory Research 2020 21:286
  21. Israel ranks very high globally in performing bariatric surgery (BS) per capita. In the first phase of the COVID-19 pandemic the bariatric surgeons’ community faced many concerns and challenges, especially in ...

    Authors: Nahum Beglaibter, Orly Zelekha, Lital Keinan-Boker, Nasser Sakran and Ahmad Mahajna
    Citation: Israel Journal of Health Policy Research 2020 9:59
  22. Interleukin-6 (IL-6) was proposed to be associated with the severity of coronavirus disease 2019 (COVID-19). The present study aimed to explore the kinetics of IL-6 levels, validate this association in COVID-1...

    Authors: Jing Zhang, Yiqun Hao, Wuling Ou, Fei Ming, Gai Liang, Yu Qian, Qian Cai, Shuang Dong, Sheng Hu, Weida Wang and Shaozhong Wei
    Citation: Journal of Translational Medicine 2020 18:406
  23. The Covid-19 pandemic is causing changes in delivery of medical care worldwide. It is not known how the management of headache patients was affected by the lockdown during the pandemic. The aim of the present ...

    Authors: Espen Saxhaug Kristoffersen, Kashif Waqar Faiz, Else Charlotte Sandset, Anette Margrethe Storstein, Simon Stefansen, Bendik Slagsvold Winsvold and Jakob Møller Hansen
    Citation: The Journal of Headache and Pain 2020 21:128

    The Correction to this article has been published in The Journal of Headache and Pain 2020 21:132

  24. The heavy reliance on remote patient care (RPC) during the COVID-19 health crisis may have expedited the emergence of digital health tools that can contribute to safely and effectively moving the locus of care...

    Authors: Shirly Bar-Lev and Dizza Beimel
    Citation: Israel Journal of Health Policy Research 2020 9:58

    The Commentary to this article has been published in Israel Journal of Health Policy Research 2021 10:21

  25. The acknowledgment of the mental health toll of the COVID-19 epidemic in healthcare workers has increased considerably as the disease evolved into a pandemic status. Indeed, high prevalence rates of depression...

    Authors: Luisa Weiner, Fabrice Berna, Nathalie Nourry, François Severac, Pierre Vidailhet and Amaury C. Mengin
    Citation: Trials 2020 21:870
  26. Prior studies reported that 5 ~ 32% COVID-19 patients were critically ill, a situation that poses great challenge for the management of the patients and ICU resources. We aim to identify independent risk facto...

    Authors: Sijing Cheng, Dingfeng Wu, Jie Li, Yifeng Zou, Yunle Wan, Lihan Shen, Lixin Zhu, Mang Shi, Linlin Hou, Tao Xu, Na Jiao, Yichen Li, Yibo Huang, Zhipeng Tang, Mingwei Xu, Shusong Jiang…
    Citation: Respiratory Research 2020 21:277
  27. Severe coronavirus disease 2019 (COVID-19) is frequently associated with hyperinflammation and hyperferritinemia. The latter is related to increased mortality in COVID-19. Still, it is not clear if iron dysmet...

    Authors: Thomas Sonnweber, Anna Boehm, Sabina Sahanic, Alex Pizzini, Magdalena Aichner, Bettina Sonnweber, Katharina Kurz, Sabine Koppelstätter, David Haschka, Verena Petzer, Richard Hilbe, Markus Theurl, Daniela Lehner, Manfred Nairz, Bernhard Puchner, Anna Luger…
    Citation: Respiratory Research 2020 21:276
  28. The Hadassah Medical Organization operates two hospitals in Jerusalem. During the COVID-19 pandemic it made an administrative decision to operate one hospital as a COVID-19 treatment hospital (CTH) and to have...

    Authors: Yael Milgrom, Yuval Tal and Aharon S. Finestone
    Citation: Israel Journal of Health Policy Research 2020 9:55
  29. There is an urgent need for treatments that can shorten hospitalization and lower the risk of secondary infection and death in patients with corona disease. The ProPac-COVID trial evaluates whether combination...

    Authors: Pradeesh Sivapalan, Charlotte Suppli Ulrik, Therese Sophie Lappere, Josefin Viktoria Eklöf, Saher Burhan Shaker, Uffe Christian Steinholtz Bødtger, Andrea Browatzki, Christian Niels Meyer, Ulla Møller Weinreich, Christian B. Laursen, Tor Biering-Sørensen, Filip Krag Knop, Jens D. Lundgren and Jens-Ulrik Stæhr Jensen
    Citation: Trials 2020 21:867

    The Letter to this article has been published in Trials 2020 21:513

  30. The outbreak of a new Coronavirus disease (COVID-19) poses dramatic challenges to public health authorities worldwide. One measure put in place to contain the spread of the disease is self-quarantine of indivi...

    Authors: Moran Bodas and Kobi Peleg
    Citation: Israel Journal of Health Policy Research 2020 9:54
  31. Facing the global health crisis of COVID-19, health systems are increasingly supporting the use of telemedicine in ambulatory care settings. It is not clear whether the increased use of telemedicine will persi...

    Authors: Zachi Grossman, Gabriel Chodick, Stephen M. Reingold, Gil Chapnick and Shai Ashkenazi
    Citation: Israel Journal of Health Policy Research 2020 9:53
  32. The understanding of coronavirus disease 2019 (COVID-19) is rapidly evolving. Although it is primarily a respiratory illness, other manifestations, such as Guillain-Barré syndrome, immune thrombocytopenia, and...

    Authors: Birgitte Tholin, Marit Teigen Hauge, Pål Aukrust, Lutz Fehrle and Tor Henrik Tvedt
    Citation: Journal of Medical Case Reports 2020 14:187
  33. COVID-19 which started in Wuhan, China and swiftly expanded geographically worldwide, including to Low to Middle Income Countries (LMICs). This in turn raised numerous ethical concerns in preparedness, knowled...

    Authors: Faouzia Tanveer, Ali Talha Khalil, Muhammad Ali and Zabta Khan Shinwari
    Citation: International Journal for Equity in Health 2020 19:182
  34. Primary objective: To determine the efficacy of a candidate antiviral on time to virological cure compared to standard of care within 14 days of randomisation

    Authors: James H. McMahon, Jillian S. Y. Lau, Janine Roney, Benjamin A. Rogers, Jason Trubiano, Joseph Sasadeusz, James S. Molton, Bradley Gardiner, Sue J. Lee, Jennifer F. Hoy, Allen Cheng and Anton Y. Peleg
    Citation: Trials 2020 21:847
  35. Patients with severe, uncontrolled asthma, particularly those with a non-eosinophilic phenotype, have a great unmet need for new treatments that act on a broad range of inflammatory pathways in the airway. Tez...

    Authors: Claire Emson, Sarah Diver, Latifa Chachi, Ayman Megally, Cherrie Small, John Downie, Jane R. Parnes, Karin Bowen, Gene Colice and Chris E. Brightling
    Citation: Respiratory Research 2020 21:265
  36. Headache is the most common COVID-19-related neurological symptom. We aimed to reveal diagnostic clues of headache for COVID-19 infection and to investigate the course of primary headaches during the pandemic.

    Authors: Özge Uygun, Mustafa Ertaş, Esme Ekizoğlu, Hayrunnisa Bolay, Aynur Özge, Elif Kocasoy Orhan, Arif Atahan Çağatay and Betül Baykan
    Citation: The Journal of Headache and Pain 2020 21:121
  37. The coronavirus disease 2019 (COVID-19) has brought a global disaster. Quantitative lesions may provide the radiological evidence of the severity of pneumonia and further to assess the effect of comorbidity on...

    Authors: Cui Zhang, Guangzhao Yang, Chunxian Cai, Zhihua Xu, Hai Wu, Youmin Guo, Zongyu Xie, Hengfeng Shi, Guohua Cheng and Jian Wang
    Citation: European Journal of Medical Research 2020 25:49
  38. SARS-CoV-2 and its associated disease, COVID-19, has infected over seven million people world-wide, including two million people in the United States. While many people recover from the virus uneventfully, a s...

    Authors: William R. Hartman, Aaron S. Hess and Joseph P. Connor
    Citation: Translational Medicine Communications 2020 5:17
  39. COVID-19 is a complex and heterogeneous disease. The pathogenesis and the complications of the disease are not fully elucidated, and increasing evidence shows that SARS-CoV-2 causes a systemic inflammatory dis...

    Authors: Stefano Aliberti, Francesco Amati, Maria Pappalettera, Marta Di Pasquale, Alice D’Adda, Marco Mantero, Andrea Gramegna, Edoardo Simonetta, Anna Maria Oneta, Emilia Privitera, Andrea Gori, Giorgio Bozzi, Flora Peyvandi, Francesca Minoia, Giovanni Filocamo, Chiara Abbruzzese…
    Citation: Respiratory Research 2020 21:260
  40. The outbreak of Coronavirus Disease is causing considerable acute risk to public health and might also have an unanticipated impact on the mental health of children and adolescents in the long run. This study ...

    Authors: Shitao Chen, Zeyuan Cheng and Jing Wu
    Citation: Globalization and Health 2020 16:96
  41. Family-based treatment (FBT) is an efficacious outpatient intervention for young people diagnosed with Anorexia Nervosa (AN). To date, treatment to protocol has relied on standard face-to-face delivery. Face-t...

    Authors: A. Hambleton, D. Le Grange, J. Miskovic-Wheatley, S. Touyz, M. Cunich and S. Maguire
    Citation: Journal of Eating Disorders 2020 8:50
  42. Coronavirus Disease 2019 (COVID-19) spread rapidly around the world. We aimed to describe the epidemiological characteristics and the entire evolution of COVID-19 in Wuhan, and to evaluate the effect of non-ph...

    Authors: Dongming Wang, Jing Cai, Tingming Shi, Yang Xiao, Xiaobing Feng, Meng Yang, Wenzhen Li, Wei Liu, Linling Yu, Zi Ye, Tao Xu, Jixuan Ma, Mingyan Li and Weihong Chen
    Citation: Respiratory Research 2020 21:257
  43. The COVID-19 pandemic disrupted the personal, professional and social life of Australians with some people more impacted than others.

    Authors: Muhammad Aziz Rahman, Nazmul Hoque, Sheikh M. Alif, Masudus Salehin, Sheikh Mohammed Shariful Islam, Biswajit Banik, Ahmed Sharif, Nashrin Binte Nazim, Farhana Sultana and Wendy Cross
    Citation: Globalization and Health 2020 16:95
  44. Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) outbreak, called coronavirus disease - 2019 (COVID-19), has affected more than 200 countries across the globe with a higher fatality rate among the ...

    Authors: Alok Ranjan and V. R. Muraleedharan
    Citation: Globalization and Health 2020 16:93
  45. According to the World Health Organization (WHO), the outbreak of coronavirus disease in 2019 (COVID-19) has been declared as a pandemic and public health emergency that infected more than 5 million people wor...

    Authors: Degena Bahrey Tadesse, Shishay Wahdey, Melaku Negash, Ebud Ayele, Teklehaimanot Gereziher Haile, Kbrom Gemechu Kiros, Yohannes Ashebir Tesfamichael and Kiros Belay Gebrekidan
    Citation: Asthma Research and Practice 2020 6:11