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Coronavirus research highlights

A novel coronavirus, 2019-nCoV, has been identified as the cause of an outbreak of respiratory illness that originated in Wuhan, China, and which has spread to several other countries around the world.  Recent content from BMC and SpringerOpen journals relevant to coronavirus research, as well as additional commentary on this topic, is included below. 

BMC, as part of Springer Nature, encourages early sharing of research submitted to all our journals through preprints, and our In Review preprint service is available for many journals. We strongly urge authors submitting articles related to this emergency to BMC journals to share underlying interim and final research datasets relating to the outbreak as rapidly and widely as possible, including with public health and research communities and the WHO.

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  1. Medical staff caring for COVID-19 patients face mental stress, physical exhaustion, separation from families, stigma, and the pain of losing patients and colleagues. Many of them have acquired SARS-CoV-2 and s...

    Authors: Matthew F. Chersich, Glenda Gray, Lee Fairlie, Quentin Eichbaum, Susannah Mayhew, Brian Allwood, Rene English, Fiona Scorgie, Stanley Luchters, Greg Simpson, Marjan Mosalman Haghighi, Minh Duc Pham and Helen Rees

    Citation: Globalization and Health 2020 16:46

    Content type: Review

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  2. The rapid spread of the corona virus pandemic is an existential problem for many people in numerous countries. So far, there is no effective vaccine protection or proven therapy available against the SARS-CoV-...

    Authors: Johannes C. Fischer, Kurt Zänker, Martijn van Griensven, Marion Schneider, Detlef Kindgen-Milles, Wolfram Trudo Knoefel, Artur Lichtenberg, Balint Tamaskovics, Freddy Joel Djiepmo-Njanang, Wilfried Budach, Stefanie Corradini, Ute Ganswindt, Dieter Häussinger, Torsten Feldt, Hubert Schelzig, Hans Bojar…

    Citation: European Journal of Medical Research 2020 25:16

    Content type: Review

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  3. We present the rationale for a novel allo-priming approach to serve the elderly as a universal anti-virus vaccine, as well serving to remodel the aging immune system in order to reverse immunosenescence and in...

    Authors: Michael Har-Noy and Reuven Or

    Citation: Journal of Translational Medicine 2020 18:196

    Content type: Review

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  4. The recent pandemic caused by the 2019 outbreak of novel coronavirus (2019-nCoV or COVID-19) has affected more than 3.0 million people resulting ~ 212,000 deaths across 215 countries/territories as on 28th Apr...

    Authors: Sachin S. Gunthe and Satya S. Patra

    Citation: Globalization and Health 2020 16:45

    Content type: Commentary

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  5. The coronavirus disease 2019 (COVID-19) is profoundly affecting life around the globe. Isolation, contact restrictions and economic shutdown impose a complete change to the psychosocial environment in affected...

    Authors: Jörg M. Fegert, Benedetto Vitiello, Paul L. Plener and Vera Clemens

    Citation: Child and Adolescent Psychiatry and Mental Health 2020 14:20

    Content type: Review

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  6. The triglyceride and glucose index (TyG) has been proposed as a marker of insulin resistance. This study aims to evaluate the association of the TyG index with the severity and mortality of coronavirus disease...

    Authors: Huihui Ren, Yan Yang, Fen Wang, Yongli Yan, Xiaoli Shi, Kun Dong, Xuefeng Yu and Shujun Zhang

    Citation: Cardiovascular Diabetology 2020 19:58

    Content type: Original investigation

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  7. COVID-19 is a rapidly spreading virus infection that has quickly caused extensive burden to individual, families, countries, and the globe. No intervention has yet been proven effective for the treatment of CO...

    Authors: Sophie Juul, Niklas Nielsen, Peter Bentzer, Areti Angeliki Veroniki, Lehana Thabane, Adam Linder, Sarah Klingenberg, Christian Gluud and Janus Christian Jakobsen

    Citation: Systematic Reviews 2020 9:108

    Content type: Protocol

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  8. The coronavirus disease 2019 (COVID-2019) pandemic struck Latin America in late February and is now beginning to spread across the rural indigenous communities in the region, home to 42 million people. Eighty ...

    Authors: Sergio Meneses-Navarro, María Graciela Freyermuth-Enciso, Blanca Estela Pelcastre-Villafuerte, Roberto Campos-Navarro, David Mariano Meléndez-Navarro and Liliana Gómez-Flores-Ramos

    Citation: International Journal for Equity in Health 2020 19:63

    Content type: Commentary

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  9. On February 19th 2020, the Iranian Ministry of Health and Medical Education (MoHME) has announced the first 2 cases of SARS-CoV-2, a novel emerging coronavirus which causes an infection termed as COVID-19, in Qom...

    Authors: Masoud Behzadifar, Mahboubeh Khaton Ghanbari, Ahad Bakhtiari, Meysam Behzadifar and Nicola Luigi Bragazzi

    Citation: International Journal for Equity in Health 2020 19:61

    Content type: Commentary

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  10. The impact of COVID-19 across health services, including treatment services for people who use drugs, is emerging but likely to have a high impact. Treatment services for people who use drugs provide essential...

    Authors: Adrian Dunlop, Buddhima Lokuge, Debbie Masters, Marcia Sequeira, Peter Saul, Grace Dunlop, John Ryan, Michelle Hall, Nadine Ezard, Paul Haber, Nicholas Lintzeris and Lisa Maher

    Citation: Harm Reduction Journal 2020 17:26

    Content type: Opinion

    Published on:

  11. A new human coronavirus named SARS-CoV-2 was identified in several cases of acute respiratory syndrome in Wuhan, China in December 2019. On March 11 2020, WHO declared the SARS-CoV-2 infection to be a pandemic...

    Authors: Luigi Buonaguro, Maria Tagliamonte, Maria Lina Tornesello and Franco M. Buonaguro

    Citation: Journal of Translational Medicine 2020 18:185

    Content type: Commentary

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  12. The outbreak of 2019 novel coronavirus disease (COVID-19) worldwide is becoming rapidly a major concern. The number of severe cases has increased dramatically worldwide, while specific treatment options are sc...

    Authors: Shan Liu, Danyi Peng, Huijun Qiu, Ke Yang, Zhou Fu and Lin Zou

    Citation: Stem Cell Research & Therapy 2020 11:169

    Content type: Commentary

    Published on:

  13. The novel coronavirus (2019-nCoV) is an emerging causative agent that was first described in late December 2019 and causes a severe respiratory infection in humans. Notably, many of affected patients of COVID-...

    Authors: Peiwei Chai, Jie Yu, Shengfang Ge, Renbing Jia and Xianqun Fan

    Citation: Journal of Hematology & Oncology 2020 13:43

    Content type: Letter to the Editor

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  14. The world is currently dominated by the Corona Virus Disease 2019 (COVID-19) pandemic. Besides the obvious concerns about limitation of virus spread and providing the best possible care to infected patients, a...

    Authors: Antoinette MaassenVanDenBrink, Tessa de Vries and A. H. Jan Danser

    Citation: The Journal of Headache and Pain 2020 21:38

    Content type: Commentary

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  15. The novel coronavirus disease (COVID-19) outbreak was first declared in China in December 2019, and WHO declared the pandemic on 11 March 2020. A fast-rising number of confirmed cases has been observed in all ...

    Authors: Kun Tang, Junjian Gaoshan, Babatunde Ahonsi, Moazzam Ali, Mercedes Bonet, Nathalie Broutet, Edna Kara, Caron Kim, Anna Thorson and Soe Soe Thwin

    Citation: Reproductive Health 2020 17:59

    Content type: Commentary

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  16. SARS-CoV-2 is a RNA coronavirus responsible for the pandemic of the Severe Acute Respiratory Syndrome (COVID-19). RNA viruses are characterized by a high mutation rate, up to a million times higher than that o...

    Authors: Maria Pachetti, Bruna Marini, Francesca Benedetti, Fabiola Giudici, Elisabetta Mauro, Paola Storici, Claudio Masciovecchio, Silvia Angeletti, Massimo Ciccozzi, Robert C. Gallo, Davide Zella and Rudy Ippodrino

    Citation: Journal of Translational Medicine 2020 18:179

    Content type: Research

    Published on:

  17. The novel coronavirus disease (COVID-19) outbreak started in December 2019 in Wuhan, China, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The CT image is used to assess the disease pr...

    Authors: Jing Gao, Jun-Qiang Liu, Heng-Jun Wen, Hua Liu, Wei-Dong Hu, Xia Han, Chuan-Xing Li and Xiao-Jun Wang

    Citation: Respiratory Research 2020 21:96

    Content type: Letter to the Editor

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  18. On March 11th, 2020 the World Health Organization declared COVID-19 a global pandemic. The infection, transmitted by 2019 novel coronavirus (2019-nCov), was first discovered in December 2019, in Wuhan, Hubei P...

    Authors: Francesco Licciardi, Teresa Giani, Letizia Baldini, Ennio Giulio Favalli, Roberto Caporali and Rolando Cimaz

    Citation: Pediatric Rheumatology 2020 18:35

    Content type: Review

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  19. The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China has been declared a public health emergency of international concern. The car...

    Authors: Lei Gao, Dan Jiang, Xue-song Wen, Xiao-cheng Cheng, Min Sun, Bin He, Lin-na You, Peng Lei, Xiao-wei Tan, Shu Qin, Guo-qiang Cai and Dong-ying Zhang

    Citation: Respiratory Research 2020 21:83

    Content type: Research

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  20. A novel coronavirus was identified in December, 2019 in Wuhan, China, and traditional Chinese medicine (TCM) played an active role in combating the novel coronavirus pneumonia (NCP) caused by this fast-spreadi...

    Authors: Erdan Luo, Daiyan Zhang, Hua Luo, Bowen Liu, Keming Zhao, Yonghua Zhao, Ying Bian and Yitao Wang

    Citation: Chinese Medicine 2020 15:34

    Content type: Research

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  21. A new type of coronavirus, novel coronavirus (COVID-19), is causing an increasing number of cases of pneumonia and was declared a Public Health Emergency of International Concern by the World Health Organizati...

    Authors: Yuxi Li, Xiaobo Liu, Liuxue Guo, Juan Li, Dongling Zhong, Yonggang Zhang, Mike Clarke and Rongjiang Jin

    Citation: Systematic Reviews 2020 9:75

    Content type: Protocol

    Published on:

  22. The outbreak of coronavirus disease 2019 (COVID-19) has caused more than 80 813 confirmed cases in all provinces of China, and 21 110 cases reported in 93 countries of six continents as of 7 March 2020 since m...

    Authors: Xu Qian, Ran Ren, Youfa Wang, Yan Guo, Jing Fang, Zhong-Dao Wu, Pei-Long Liu and Tie-Ru Han

    Citation: Infectious Diseases of Poverty 2020 9:34

    Content type: Commentary

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  23. Since the first case of a coronavirus disease 2019 (COVID-19) infection pneumonia was detected in Wuhan, China, a series of confirmed cases of the COVID-19 were found in Southwest China. The aim of this study ...

    Authors: Xiaoming Li, Wenbing Zeng, Xiang Li, Haonan Chen, Linping Shi, Xinghui Li, Hongnian Xiang, Yang Cao, Hui Chen, Chen Liu and Jian Wang

    Citation: Journal of Translational Medicine 2020 18:154

    Content type: Research

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  24. Coronavirus can cross the species barrier and infect humans with a severe respiratory syndrome. SARS-CoV-2 with potential origin of bat is still circulating in China. In this study, a prediction model is propo...

    Authors: Xiao-Li Qiang, Peng Xu, Gang Fang, Wen-Bin Liu and Zheng Kou

    Citation: Infectious Diseases of Poverty 2020 9:33

    Content type: Research Article

    Published on:

  25. The coronavirus disease (COVID-19) has been identified as the cause of an outbreak of respiratory illness in Wuhan, Hubei Province, China beginning in December 2019. As of 31 January 2020, this epidemic had sp...

    Authors: Sasmita Poudel Adhikari, Sha Meng, Yu-Ju Wu, Yu-Ping Mao, Rui-Xue Ye, Qing-Zhi Wang, Chang Sun, Sean Sylvia, Scott Rozelle, Hein Raat and Huan Zhou

    Citation: Infectious Diseases of Poverty 2020 9:29

    Content type: Scoping Review

    Published on:

  26. In December 2019, a new virus (initially called ‘Novel Coronavirus 2019-nCoV’ and later renamed to SARS-CoV-2) causing severe acute respiratory syndrome (coronavirus disease COVID-19) emerged in Wuhan, Hubei P...

    Authors: Maged N. Kamel Boulos and Estella M. Geraghty

    Citation: International Journal of Health Geographics 2020 19:8

    Content type: Editorial

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  27. As reported by the World Health Organization, a novel coronavirus (2019-nCoV) was identified as the causative virus of Wuhan pneumonia of unknown etiology by Chinese authorities on 7 January, 2020. The virus w...

    Authors: Tian-Mu Chen, Jia Rui, Qiu-Peng Wang, Ze-Yu Zhao, Jing-An Cui and Ling Yin

    Citation: Infectious Diseases of Poverty 2020 9:24

    Content type: Research Article

    Published on:

  28. In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province; and then named “2019 novel coronavirus (2019-nCoV)” by the World Health Organization (WHO) on 12 January 2020. For it is a ...

    Authors: Ying-Hui Jin, Lin Cai, Zhen-Shun Cheng, Hong Cheng, Tong Deng, Yi-Pin Fan, Cheng Fang, Di Huang, Lu-Qi Huang, Qiao Huang, Yong Han, Bo Hu, Fen Hu, Bing-Hui Li, Yi-Rong Li, Ke Liang…

    Citation: Military Medical Research 2020 7:4

    Content type: Position article and guideline

    Published on:

    The Commentary to this article has been published in Military Medical Research 2020 7:16

  29. Recurring outbreaks of emerging and re-emerging zoonoses, such as Ebola virus disease, avian influenza, and Nipah virus, serve as a reminder that the health of humans, animals, and the environment are intercon...

    Authors: Terra R. Kelly, Catherine Machalaba, William B. Karesh, Paulina Zielinska Crook, Kirsten Gilardi, Julius Nziza, Marcela M. Uhart, Erika Alandia Robles, Karen Saylors, Damien O. Joly, Corina Monagin, Prime Mulembakani Mangombo, Placide Mbala Kingebeni, Rudovick Kazwala, David Wolking, Woutrina Smith…

    Citation: One Health Outlook 2020 2:1

    Content type: Review

    Published on:

  30. It has been 8 years since the first case of Middle East respiratory syndrome coronavirus (MERS-CoV) was reported in Saudi Arabia and the disease is still being reported in 27 countries; however, there is no in...

    Authors: Maryam Salamatbakhsh, Kazhal Mobaraki, Sara Sadeghimohammadi and Jamal Ahmadzadeh

    Citation: BMC Public Health 2019 19:1523

    Content type: Research article

    Published on:

  31. Mortality is high among patients with Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection. We aimed to determine hospital mortality and the factors associated with it in a cohort of MERS-CoV pati...

    Authors: Abdulrahman Mohammed G. Habib, Mohamed Abd Elghafour Ali, Baha R. Zouaoui, Mustafa Ahmed H. Taha, Bassem Sahsah Mohammed and Nazmus Saquib

    Citation: BMC Infectious Diseases 2019 19:870

    Content type: Research article

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  32. We sought to assess reporting in China’s Pneumonia of Unknown Etiology (PUE) passive surveillance system for emerging respiratory infections and to identify ways to improve the PUE surveillance system’s detect...

    Authors: Nijuan Xiang, Ying Song, Yu Wang, Jiabing Wu, Alexander J. Millman, Carolyn M. Greene, Zhentao Ding, Jie Sun, Wei Yang, Guoxia Guo, Ruirui Wang, Ping Guo, Zhixing Ren, Lei Gong, Pengpeng Xu, Suizan Zhou…

    Citation: BMC Infectious Diseases 2019 19:770

    Content type: Research article

    Published on:

  33. Transmissible gastroenteritis virus (TGEV), a member of the family Coronaviridae, causes lethal watery diarrhea in piglets. Previous studies have revealed that the coronaviruses develop various strategies to evad...

    Authors: Yanan Wang, Aoying Sun, Yu Sun, Sijia Zhang, Tian Xia, Tiantian Guo, Zhenye Hao, Li Sun, Yanping Jiang, Xinyuan Qiao, Wen Cui, Lijie Tang, Yigang Xu, Yijing Li and Li Wang

    Citation: Virology Journal 2019 16:97

    Content type: Research

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  34. Coronaviruses (CoVs) primarily cause enzootic infections in birds and mammals but, in the last few decades, have shown to be capable of infecting humans as well. The outbreak of severe acute respiratory syndro...

    Authors: Dewald Schoeman and Burtram C. Fielding

    Citation: Virology Journal 2019 16:69

    Content type: Review

    Published on:

  35. Middle East respiratory syndrome coronavirus (MERS-CoV) is considered to be responsible for a new viral epidemic and an emergent threat to global health security. This study describes the current epidemiologic...

    Authors: Kazhal Mobaraki and Jamal Ahmadzadeh

    Citation: BMC Infectious Diseases 2019 19:351

    Content type: Research article

    Published on:

  36. International and national travelling has made the rapid spread of infectious diseases possible. Little information is available on the role of major traffic hubs, such as airports, in the transmission of resp...

    Authors: Niina Ikonen, Carita Savolainen-Kopra, Joanne E. Enstone, Ilpo Kulmala, Pertti Pasanen, Anniina Salmela, Satu Salo, Jonathan S. Nguyen-Van-Tam and Petri Ruutu

    Citation: BMC Infectious Diseases 2018 18:437

    Content type: Research article

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  37. Since Middle East respiratory syndrome (MERS) infection was first reported in 2012, many studies have analysed its transmissibility and severity. However, the methodology and results of these studies have vari...

    Authors: Ji-Eun Park, Soyoung Jung, Aeran Kim and Ji-Eun Park

    Citation: BMC Public Health 2018 18:574

    Content type: Research article

    Published on:

  38. Singapore remains vulnerable to worldwide epidemics due to high air traffic with other countries This study aims to measure the public’s awareness of the Middle East Respiratory Syndrome (MERS) and Avian Influ...

    Authors: Yan’an Hou, Yi-roe Tan, Wei Yen Lim, Vernon Lee, Linda Wei Lin Tan, Mark I-Cheng Chen and Peiling Yap

    Citation: BMC Public Health 2018 18:436

    Content type: Research article

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  39. Bats are natural reservoirs for several highly pathogenic and novel viruses including coronaviruses (CoVs) (mainly Alphacoronavirus and Betacoronavirus). Lyle’s flying fox (Pteropus lylei)‘s roosts and foraging s...

    Authors: Supaporn Wacharapluesadee, Prateep Duengkae, Aingorn Chaiyes, Thongchai Kaewpom, Apaporn Rodpan, Sangchai Yingsakmongkon, Sininat Petcharat, Patcharakiti Phengsakul, Pattarapol Maneeorn and Thiravat Hemachudha

    Citation: Virology Journal 2018 15:38

    Content type: Research

    Published on:

  40. Media and World Health Organization (WHO) attention on Zika virus transmission at the 2016 Rio Olympic Games and the 2015 Ebola virus outbreak in West Africa diverted the attention of global public health auth...

    Authors: Alimuddin Zumla, Abdulaziz N. Alagaili, Matthew Cotten and Esam I. Azhar

    Citation: BMC Medicine 2016 14:132

    Content type: Commentary

    Published on:

  41. An outbreak of the Middle East respiratory syndrome (MERS), comprising 185 cases linked to healthcare facilities, occurred in the Republic of Korea from May to July 2015. Owing to the nosocomial nature of the ...

    Authors: Kenji Mizumoto, Akira Endo, Gerardo Chowell, Yuichiro Miyamatsu, Masaya Saitoh and Hiroshi Nishiura

    Citation: BMC Medicine 2015 13:228

    Content type: Research article

    Published on: