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COVID-19: Its Pathogenetic Mechanisms and Potential Therapeutics

We are pleased to announce that the special issue of Inflammation and Regeneration, entitled “COVID-19: Its Pathogenetic Mechanisms and Potential Therapeutics” has now published in the autumn of 2020. Obviously, the suppression of COVID-19 is an urgent task for all humankind, but even if this is achieved, we must be prepared for any future pandemics triggered by other pathogens. To do this, it is crucial to establish diagnostic, therapeutic, and prophylactic methods, including vaccines, for COVID-19. In this special issue, we invited 8 leading researchers to overview the cutting-edge COVID-19-related studies. In addition, we have opened a call for submissions reporting ongoing medical research in wide range of topics related to COVID-19.

This special issue includes articles related to i) The basic properties and epidemiology of SARS-CoV-2; ii) Pathological mechanisms of COVID-19, iii) Diagnosis of COVID-19 and detection of SARS-CoV-2 (8); iv) Potential therapeutics for COVID-19.

Here, we would like to make a most cordial acknowledgement to the researchers who contributed to this special issue and sincerely hope that these articles will provide novel insights for the suppression of COVID-19 and future pandemics.

November 1, 2020

Guest Editors
Hideyuki Okano
Ken-ichiro Seino

  1. Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first emerged in Wuhan, China, and has spread globally to most countries. In Japan, the first COVID-...

    Authors: Tokio Hoshina, Hiroka Aonuma, Manabu Ote, Tatsuya Sakurai, Erisha Saiki, Yuki Kinjo, Kazuhiro Kondo, Masataka Okabe and Hirotaka Kanuka

    Citation: Inflammation and Regeneration 2020 40:38

    Content type: Review

    Published on:

  2. In this review article, it is highlighted the implications of pleiotropic functions of interleukin-6 (IL-6) for one of the therapeutic options targeting for COVID-19. Moreover, it is discussed how real-world d...

    Authors: Misato Hashizume

    Citation: Inflammation and Regeneration 2020 40:24

    Content type: Review

    Published on:

  3. The newly emerging coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan, China, but has rapidly spread all over the world. Some...

    Authors: Shintaro Hojyo, Mona Uchida, Kumiko Tanaka, Rie Hasebe, Yuki Tanaka, Masaaki Murakami and Toshio Hirano

    Citation: Inflammation and Regeneration 2020 40:37

    Content type: Review

    Published on:

  4. The COVID-19 pandemic highlighted the vulnerability of every aspect of the globalized world, including R&D. Potentially critical R&D areas have been neglected because of the lack of market-driven incentives. H...

    Authors: Hiroki Nakatani, Kei Katsuno and Hayato Urabe

    Citation: Inflammation and Regeneration 2020 40:34

    Content type: Review

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  5. It has been reported that coronavirus disease 2019 (COVID-19) causes not only pneumonia but also systemic inflammations including central nervous system (CNS) disorders. However, little is known about the mech...

    Authors: Yoshitaka Kase and Hideyuki Okano

    Citation: Inflammation and Regeneration 2020 40:32

    Content type: Rapid communication

    Published on:

  6. Coronavirus disease of 2019 (COVID-19), which originated in China in 2019, shows mild cold and pneumonia symptoms that can occasionally worsen and result in deaths. SARS-CoV-2 was reported to be the causative ...

    Authors: So Nakagawa and Takayuki Miyazawa

    Citation: Inflammation and Regeneration 2020 40:17

    Content type: Review

    Published on:

    The Correction to this article has been published in Inflammation and Regeneration 2020 40:41

  7. An emerging, rapidly spreading coronavirus SARS-CoV-2 is causing a devastating pandemic. As we have not developed curative medicine and effective vaccine, the end of this life-threatening infectious disease is...

    Authors: Ryo Otsuka and Ken-ichiro Seino

    Citation: Inflammation and Regeneration 2020 40:19

    Content type: Review

    Published on:

  8. The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19) and the ensuing worldwide pandemic. The spread of the virus has ...

    Authors: Atsunori Tsuchiya, Suguru Takeuchi, Takahiro Iwasawa, Masaru Kumagai, Takeki Sato, Satoko Motegi, Yui Ishii, Youhei Koseki, Kei Tomiyoshi, Kazuki Natsui, Nobutaka Takeda, Yuki Yoshida, Fusako Yamazaki, Yuichi Kojima, Yusuke Watanabe, Naruhiro Kimura…

    Citation: Inflammation and Regeneration 2020 40:14

    Content type: Review

    Published on:

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