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Comparative Immunosenescence

Topical Collection for Immunity & Ageing: Comparative Immunosenescense

Edited by:
Graham Pawelec, MA, PhD (Cantab), University of Tübingen, Germany. 

Graham Pawelec is Professor of Experimental Immunology at the University of Tübingen, Germany, where he led the Tübingen Ageing and Tumour Immunology (TATI) group from 1999 to 2017. He is currently affiliated with the Health Sciences North Research Institute of Canada, Sudbury, ON, and is a Visiting Professor at Nottingham Trent University, King´s College London, and Manchester University, UK. His research interests remain centered on immunogerontology in the context of cancer immunology and immunotherapy, and vaccination.

Comparative Immunosenescense is a topical collection of the journal Immunity & Ageing. Our knowledge of the negative consequences of the important differences of immune function seen in younger and older individuals is scarce, and mostly limited to humans, mice and to some extent monkeys and companion animals. However, comparative studies of the health impacts of immune ageing in other species, potentially including invertebrates, and in kingdoms other than animals, are scarcer still, but might shed light on some common features required for survival in a dangerous world. This Topical Collection accordingly aims to solicit papers on any aspect of immune ageing in species other than humans and mice. Reviews, original articles, commentaries, hypotheses and opinion pieces are all very welcome.

This collection of articles has not been sponsored and articles have undergone the journal’s standard peer-review process.

Please find out more about our journal and its policies, here. Submission guidelines can be found here, and please submit to the collection via our submission system (there will be a field for which you can indicate if you are submitting to this collection).

  1. The Disposable Soma Theory of aging suggests a trade-off between energy allocation for growth, reproduction and somatic maintenance, including immunity. While trade-offs between reproduction and immunity are w...

    Authors: Agathe Crosland, Thierry Rigaud, Charlène Develay and Yannick Moret
    Citation: Immunity & Ageing 2024 21:7
  2. The progressive deregulation of the immune system with age, termed immunosenescence, has been well studied in mammalian systems, but studies of immune function in long-lived, wild, non-mammalian populations ar...

    Authors: Anne M. Bronikowski, Ashley R. Hedrick, Greta A. Kutz, Kaitlyn G. Holden, Beth Reinke and John B. Iverson
    Citation: Immunity & Ageing 2023 20:11
  3. The equine population in the United States and worldwide now includes a higher percentage of geriatric horses than ever previously recorded, and as methods to treat and manage elderly equids are developed and ...

    Authors: Sally DeNotta and Dianne McFarlane
    Citation: Immunity & Ageing 2023 20:2
  4. Immunosenescence is an age-dependent decline in immune functions and hallmark of aging in diverse species, ranging from invertebrates to mammals. However, identifying the factors responsible for immunosenescen...

    Authors: Sieun S. Kim, Jooyeon Sohn and Seung-Jae V. Lee
    Citation: Immunity & Ageing 2022 19:56