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Communications in Epigenetics: state of the art and beyond in chromatin biology and pathophysiology

New Content ItemCollection closed for submissions

We are proud to announce a new cross-journal thematic series between Springer Nature’s Clinical Epigenetics and Epigenetics Communications, guest edited by Renata Z. Jurkowska, Frank Johannes and Tomasz K. Wojdacz. This series was inspired by vibrant discussions at the inaugural edition of the Clinical Epigenetics & Epigenetics Communication International Conference (CLEPIC) in June 2022 in Poland and will cover the latest advances in epigenetic research, ranging from basic epigenetic mechanisms across different organisms to applied clinical epigenetics.

Potential topics include, but are not limited to:

Epigenetic Mechanisms
Epigenetics of Disease
Epigenetic Biomarkers
Epigenetic Drugs
Cancer Epigenetics
Epigenomic Approaches across the tree of life
Computational Analysis of Epigenomes
Epigenetics in Development and Ageing

We accept original research articles, reviews, perspectives, and opinion articles. For our recently launched Epigenetics Communications journal, we explicitly welcome well-executed studies that showcase and discuss alternative conclusions/interpretations of well-established epigenetic phenomena, as well as technically sound studies that “fail” to prove a scientific hypothesis (so-called “negative data”). Altogether, we aim for this Series to provide a comprehensive reference work of the many exciting developments in the field.

Inquiries can be made to Renata Z. Jurkowska (, Frank Johannes ( and Tomasz K. Wojdacz (

  1. Screening plays a key role in secondary prevention of cervical cancer. High-risk human papillomavirus (hrHPV) testing, a highly sensitive test but with limited specificity, has become the gold standard frontli...

    Authors: Sofia Salta, João Lobo, Bruno Magalhães, Rui Henrique and Carmen Jerónimo
    Citation: Clinical Epigenetics 2023 15:125
  2. Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder characterized by chronic low-grade inflammation. Previous studies have demonstrated that the gut microbiome can affect the host tissue ce...

    Authors: Kailu Liu, Xi He, Jingyu Huang, Simin Yu, Meiting Cui, Mengya Gao, Li Liu, Yu Qian, Ying Xie, Miao Hui, Yanli Hong and Xiaowei Nie
    Citation: Clinical Epigenetics 2023 15:86
  3. Chromatin regulators (CRs) are critical epigenetic modifiers and have been reported to play critical roles during the progression of various tumors, but their role in lung adenocarcinoma (LUAD) has not been co...

    Authors: Yongbiao Huang, Lingyan Xiao, Motuma Yigezu Daba, Duo Xu, Yuan Wang, Long Li, Qian Li, Bo Liu, Wan Qin, Huixian Zhang and Xianglin Yuan
    Citation: Clinical Epigenetics 2023 15:72
  4. Epigenetic age acceleration (EAA) and epigenetic gestational age acceleration (EGAA) are biomarkers of physiological development and may be affected by the perinatal environment. The aim of this study was to e...

    Authors: Anne K. Bozack, Sheryl L. Rifas-Shiman, Diane R. Gold, Zachary M. Laubach, Wei Perng, Marie-France Hivert and Andres Cardenas
    Citation: Clinical Epigenetics 2023 15:62
  5. The protocadherin proteins are cell adhesion molecules at the crossroad of signaling pathways playing a major role in neuronal development. It is now understood that their role as signaling hubs is not only im...

    Authors: Arnaud Carrier, Cécile Desjobert, Valérie Lobjois, Lise Rigal, Florence Busato, Jörg Tost, Miquel Ensenyat-Mendez, Diego M. Marzese, Anne Pradines, Gilles Favre, Laurence Lamant, Luisa Lanfrancone, Chantal Etievant, Paola B. Arimondo and Joëlle Riond
    Citation: Clinical Epigenetics 2022 14:156
  6. Cystoscopy is the gold standard for bladder cancer detection, but is costly, invasive and has imperfect diagnostic accuracy. We aimed to identify novel and accurate DNA methylation biomarkers for non-invasive ...

    Authors: Heidi Dietrichson Pharo, Marine Jeanmougin, Eirill Ager-Wick, Hege Marie Vedeld, Anne Klara Sørbø, Christina Dahl, Louise Katrine Larsen, Hilde Honne, Sara Brandt-Winge, May-Britt Five, Sara Monteiro-Reis, Rui Henrique, Carmen Jeronimo, Kenneth Steven, Rolf Wahlqvist, Per Guldberg…
    Citation: Clinical Epigenetics 2022 14:115