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Chemicals and Bioproducts from Biomass

Recently, Biotechnology for Biofuels took the decision to widen its scope to also include articles on the biological production of chemicals and bioproducts derived from biomass and CO2. Whereas a large proportion of the articles in Biotechnology for Biofuels still deal with the pretreatment, hydrolysis and bioconversion of lignocellulosic biomass to ethanol, the journal also has published a number of interesting articles related to bio-based chemicals and other bioproducts. This retrospective thematic issue assembles recent articles since 2015 to highlight these areas of research.

Edited by James du Preez

  1. Research

    The synthetic xylulose-1 phosphate pathway increases production of glycolic acid from xylose-rich sugar mixtures

    Glycolic acid (GA) is a two-carbon hydroxyacid with applications in the cosmetic, textile, and medical industry. Microbial GA production from all sugars can be achieved by engineering the natural glyoxylate sh...

    Ceren Alkim, Debora Trichez, Yvan Cam, Lucie Spina, Jean Marie François and Thomas Walther

    Biotechnology for Biofuels 2016 9:201

    Published on: 20 September 2016

  2. Research

    Metabolic engineering of Zymomonas mobilis for 2,3-butanediol production from lignocellulosic biomass sugars

    To develop pathways for advanced biofuel production, and to understand the impact of host metabolism and environmental conditions on heterologous pathway engineering for economic advanced biofuels production f...

    Shihui Yang, Ali Mohagheghi, Mary Ann Franden, Yat-Chen Chou, Xiaowen Chen, Nancy Dowe, Michael E. Himmel and Min Zhang

    Biotechnology for Biofuels 2016 9:189

    Published on: 2 September 2016

  3. Research

    Robust succinic acid production from crude glycerol using engineered Yarrowia lipolytica

    Integrating waste management with fuels and chemical production is considered to address the food waste problem and oil crisis. Approximately, 600 million tonnes crude glycerol is produced from the biodiesel i...

    Cuijuan Gao, Xiaofeng Yang, Huaimin Wang, Cristina Perez Rivero, Chong Li, Zhiyong Cui, Qingsheng Qi and Carol Sze Ki Lin

    Biotechnology for Biofuels 2016 9:179

    Published on: 30 August 2016

  4. Research

    A novel strain of Yarrowia lipolytica as a platform for value-added product synthesis from glycerol

    Increasing interest of non-conventional yeasts has been observed for many years due to their biochemical characteristics and potential applications. Well-studied, oleaginous yeast Y. lipolytica is an attractive h...

    Aleksandra M. Mirończuk, Dorota A. Rzechonek, Anna Biegalska, Magdalena Rakicka and Adam Dobrowolski

    Biotechnology for Biofuels 2016 9:180

    Published on: 30 August 2016

  5. Research

    Elucidation of the co-metabolism of glycerol and glucose in Escherichia coli by genetic engineering, transcription profiling, and 13C metabolic flux analysis

    Glycerol, a byproduct of biodiesel, has become a readily available and inexpensive carbon source for the production of high-value products. However, the main drawback of glycerol utilization is the low consump...

    Ruilian Yao, Dewang Xiong, Hongbo Hu, Masataka Wakayama, Wenjuan Yu, Xuehong Zhang and Kazuyuki Shimizu

    Biotechnology for Biofuels 2016 9:175

    Published on: 22 August 2016

  6. Research

    Enhanced malic acid production from glycerol with high-cell density Ustilago trichophora TZ1 cultivations

    In order to establish a cost-efficient biodiesel biorefinery, valorization of its main by-product, crude glycerol, is imperative. Recently, Ustilago trichophora TZ1 was found to efficiently produce malic acid fro...

    Thiemo Zambanini, Wiebke Kleineberg, Eda Sarikaya, Joerg M. Buescher, Guido Meurer, Nick Wierckx and Lars M. Blank

    Biotechnology for Biofuels 2016 9:135

    Published on: 2 July 2016

  7. Research

    Engineering Bacillus licheniformis for the production of meso-2,3-butanediol

    2,3-Butanediol (2,3-BD) can be used as a liquid fuel additive to replace petroleum oil, and as an important platform chemical in the pharmaceutical and plastic industries. Microbial production of 2,3-BD by Bacill...

    Yimin Qiu, Jinyan Zhang, Lu Li, Zhiyou Wen, Christopher T. Nomura, Shuilin Wu and Shouwen Chen

    Biotechnology for Biofuels 2016 9:117

    Published on: 2 June 2016

  8. Research

    Insights into isoprene production using the cyanobacterium Synechocystis sp. PCC 6803

    Cyanobacteria are phototrophic prokaryotes that convert inorganic carbon as CO2 into organic compounds at the expense of light energy. They need only inorganic nutrients and can be cultivated to high densities us...

    Nadin Pade, Sabrina Erdmann, Heike Enke, Frederik Dethloff, Ulf Dühring, Jens Georg, Juliane Wambutt, Joachim Kopka, Wolfgang R. Hess, Ralf Zimmermann, Dan Kramer and Martin Hagemann

    Biotechnology for Biofuels 2016 9:89

    Published on: 18 April 2016

  9. Research

    Efficient malic acid production from glycerol with Ustilago trichophora TZ1

    The large surplus of crude glycerol, as main low-value waste stream in biodiesel production, has led to the investigation of new possibilities for the production of value-added chemicals from this feedstock. N...

    Thiemo Zambanini, Eda Sarikaya, Wiebke Kleineberg, Joerg M. Buescher, Guido Meurer, Nick Wierckx and Lars M. Blank

    Biotechnology for Biofuels 2016 9:67

    Published on: 17 March 2016

  10. Research

    Engineering Escherichia coli for high-yield geraniol production with biotransformation of geranyl acetate to geraniol under fed-batch culture

    Geraniol is an acyclic monoterpene alcohol, which exhibits good prospect as a gasoline alternative. Geraniol is naturally encountered in plants at low concentrations and an attractive target for microbial engi...

    Wei Liu, Xin Xu, Rubing Zhang, Tao Cheng, Yujin Cao, Xiaoxiao Li, Jiantao Guo, Huizhou Liu and Mo Xian

    Biotechnology for Biofuels 2016 9:58

    Published on: 11 March 2016

    The Erratum to this article has been published in Biotechnology for Biofuels 2016 9:131

  11. Research

    Engineering transcription factors to improve tolerance against alkane biofuels in Saccharomyces cerevisiae

    Biologically produced alkanes can be used as ‘drop in’ to existing transportation infrastructure as alkanes are important components of gasoline and jet fuels. Despite the reported microbial production of alka...

    Hua Ling, Nina Kurniasih Pratomo Juwono, Wei Suong Teo, Ruirui Liu, Susanna Su Jan Leong and Matthew Wook Chang

    Biotechnology for Biofuels 2015 8:231

    Published on: 30 December 2015

  12. Research

    Enhanced short chain fatty acids production from waste activated sludge conditioning with typical agricultural residues: carbon source composition regulates community functions

    A wide range of value-added by-products can be potentially produced from waste activated sludge (WAS) through anaerobic fermentation, among which short-chain fatty acids (SCFAs) are versatile green chemicals,...

    Zechong Guo, Aijuan Zhou, Chunxue Yang, Bin Liang, Thangavel Sangeetha, Zhangwei He, Ling Wang, Weiwei Cai, Aijie Wang and Wenzong Liu

    Biotechnology for Biofuels 2015 8:192

    Published on: 25 November 2015

    The Erratum to this article has been published in Biotechnology for Biofuels 2016 9:65

  13. Research

    Continuous succinic acid production by Actinobacillus succinogenes on xylose-enriched hydrolysate

    Bio-manufacturing of high-value chemicals in parallel to renewable biofuels has the potential to dramatically improve the overall economic landscape of integrated lignocellulosic biorefineries. However, this w...

    Michael F. A. Bradfield, Ali Mohagheghi, Davinia Salvachúa, Holly Smith, Brenna A. Black, Nancy Dowe, Gregg T. Beckham and Willie Nicol

    Biotechnology for Biofuels 2015 8:181

    Published on: 14 November 2015

  14. Research

    Lipid production in association of filamentous fungi with genetically modified cyanobacterial cells

    Numerous strategies have evolved recently for the generation of genetically modified or synthetic microalgae and cyanobacteria designed for production of ethanol, biodiesel and other fuels. In spite of their o...

    Ana F. Miranda, Mohamed Taha, Digby Wrede, Paul Morrison, Andrew S. Ball, Trevor Stevenson and Aidyn Mouradov

    Biotechnology for Biofuels 2015 8:179

    Published on: 5 November 2015

  15. Research

    Inducible gene expression system by 3-hydroxypropionic acid

    3-Hydroxypropionic acid (3-HP) is an important platform chemical that boasts a variety of industrial applications. Gene expression systems inducible by 3-HP, if available, are of great utility for optimization...

    Shengfang Zhou, Satish Kumar Ainala, Eunhee Seol, Trinh Thi Nguyen and Sunghoon Park

    Biotechnology for Biofuels 2015 8:169

    Published on: 20 October 2015

  16. Research

    High production of 2,3-butanediol from biodiesel-derived crude glycerol by metabolically engineered Klebsiella oxytoca M1

    2,3-Butanediol (2,3-BDO) is a promising bio-based chemical because of its wide industrial applications. Previous studies on microbial production of 2,3-BDO has focused on sugar fermentation. Alternatively, bio...

    Sukhyeong Cho, Taeyeon Kim, Han Min Woo, Yunje Kim, Jinwon Lee and Youngsoon Um

    Biotechnology for Biofuels 2015 8:146

    Published on: 15 September 2015

  17. Research article

    Assembly of lipase and P450 fatty acid decarboxylase to constitute a novel biosynthetic pathway for production of 1-alkenes from renewable triacylglycerols and oils

    Biogenic hydrocarbons (biohydrocarbons) are broadly accepted to be the ideal ‘drop-in’ biofuel alternative to petroleum-based fuels due to their highly similar chemical composition and physical characteristics...

    Jinyong Yan, Yi Liu, Cong Wang, Bingnan Han and Shengying Li

    Biotechnology for Biofuels 2015 8:34

    Published on: 26 February 2015

  18. Research article

    Simultaneous improvement in production of microalgal biodiesel and high-value alpha-linolenic acid by a single regulator acetylcholine

    Photoautotrophic microalgae are a promising avenue for sustained biodiesel production, but are compromised by low yields of biomass and lipids at present. We are developing a chemical approach to improve micro...

    Ali Parsaeimehr, Zhilan Sun, Xiao Dou and Yi-Feng Chen

    Biotechnology for Biofuels 2015 8:11

    Published on: 29 January 2015