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G&E Best Paper Award collection

award © JEMSEach year, G&E Editorial Board selects 'Best Paper' from the articles and short reports published in Genes and Environment in the preceding year. 

We are pleased to present here a collection of award papers since 2015. 

  1. Mutagenicity, the ability of chemical agents to cause mutations and potentially lead to cancer, is a critical aspect of substance safety assessment for protecting human health and the environment. Metabolic en...

    Authors: Kazuki Izawa, Masataka Tsuda, Takayoshi Suzuki, Masamitsu Honma and Kei-ichi Sugiyama
    Citation: Genes and Environment 2023 45:30
  2. Urea (Ua) is produced in DNA as the result of oxidative damage to thymine and guanine. It was previously reported that Klenow fragment (Kf) exo incorporated dATP opposite Ua, and that DNA polymerase β was blocke...

    Authors: Taishu Kawada, Katsuhito Kino, Kyousuke Tokorodani, Ryuto Anabuki, Masayuki Morikawa, Takanobu Kobayashi, Kazuaki Ohara, Takayuki Ohshima and Hiroshi Miyazawa
    Citation: Genes and Environment 2022 44:7
  3. The PIG-A gene mutation assay is a valuable tool for measuring in vivo gene mutations in blood cells. The human PIG-A assay, used as a potential genotoxicity biomarker, is minimally invasive, sensitive, and cost-...

    Authors: Yiyi Cao, Jing Xi, Chuanxi Tang, Ziying Yang, Weiying Liu, Xinyue You, Nannan Feng, Xin Yu Zhang, Jingui Wu, Yingxin Yu and Yang Luan
    Citation: Genes and Environment 2021 43:54
  4. Acetaldehyde, produced upon exposure to alcohol, cigarette smoke, polluted air and sugar, is a highly reactive compound that is carcinogenic to humans and causes a variety of DNA lesions in living human cells....

    Authors: Haruka Tsuruta, Yuina Sonohara, Kosuke Tohashi, Narumi Aoki Shioi, Shigenori Iwai and Isao Kuraoka
    Citation: Genes and Environment 2020 42:2
  5. Frustrated phagocytosis occurs when an asbestos fiber > 10 μm in length is engulfed imperfectly by a macrophage, and it is believed to be associated with chromosomal instability. Few studies have focused on dy...

    Authors: Takenori Ishida, Nobutoshi Fujihara, Tomoki Nishimura, Hisakage Funabashi, Ryuichi Hirota, Takeshi Ikeda and Akio Kuroda
    Citation: Genes and Environment 2019 41:14
  6. Oxidative stress leads to many kinds of diseases. Currently, urinary 8-hydroxydeoxyguanosine (8-OHdG) is widely measured as an oxidative stress biomarker. There is a specific advantage if saliva can be used as...

    Authors: Kazuaki Kawai, Hiroshi Kasai, Yun-Shan Li, Yuya Kawasaki, Shintaro Watanabe, Masanori Ohta, Toru Honda and Hiroshi Yamato
    Citation: Genes and Environment 2018 40:5
  7. Interactions between genes and environment are critical factors for causing cancer in humans. The genotoxicity of environmental chemicals can be enhanced via the modulation of susceptible genes in host human c...

    Authors: Yuki Kanemaru, Tetsuya Suzuki, Akira Sassa, Kyomu Matsumoto, Noritaka Adachi, Masamitsu Honma, Satoshi Numazawa and Takehiko Nohmi
    Citation: Genes and Environment 2017 39:6
  8. Cytosine residues in CpG dinucleotides often undergo various types of modification, such as methylation, deamination, and halogenation. These types of modifications can be pro-mutagenic and can contribute to t...

    Authors: Akira Sassa, Yuki Kanemaru, Nagisa Kamoshita, Masamitsu Honma and Manabu Yasui
    Citation: Genes and Environment 2016 38:17
  9. Asian dust events, transport of dust particles from arid and semi-arid areas in China and Mongolia to the east by prevailing westerlies, are often observed in Japan in spring. In recent decades, consumption of...

    Authors: Souleymane Coulibaly, Hiroki Minami, Maho Abe, Tomohiro Hasei, Tadashi Oro, Kunihiro Funasaka, Daichi Asakawa, Masanari Watanabe, Naoko Honda, Keiji Wakabayashi and Tetsushi Watanabe
    Citation: Genes and Environment 2015 37:25