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The genetic basis of mood and anxiety disorders

Large-scale genetic association studies published over the last few years indicate that main effects of common variants are difficult to identify in mood and anxiety disorders, suggesting that additional approaches are needed. This series aims to provide a widely accessible forum for the presentation and discussion of advances and approaches for mapping the genetic basis of mood and anxiety disorders. Articles included will highlight the use of alternative phenotypes to categorical disease constructs including dimensional behavioural and neurobiological endophenotypes, as well as translational approaches integrating animal and human data along with measures of environmental exposure and functional annotation of specific variants. Research and review articles can still be submitted for consideration in the series. Please submit online, stating clearly in the cover letter that the article should be considered for the thematic series.

Dr Elisabeth Binder

  1. Content type: Review

    Considerable variation is evident in response to psychological therapies for mood and anxiety disorders. Genetic factors alongside environmental variables and gene-environment interactions are implicated in th...

    Authors: Kathryn J Lester and Thalia C Eley

    Citation: Biology of Mood & Anxiety Disorders 2013 3:4

    Published on:

  2. Content type: Research

    Recent studies implicate individual differences in regulatory focus as contributing to self-regulatory dysfunction, particularly not responding to positive outcomes. How such individual differences emerge, howeve...

    Authors: Elena L Goetz, Ahmad R Hariri, Diego A Pizzagalli and Timothy J Strauman

    Citation: Biology of Mood & Anxiety Disorders 2013 3:3

    Published on:

  3. Content type: Research

    Posttraumatic stress disorder (PTSD) is a debilitating anxiety disorder. Surveys of the general population suggest that while 50-85% of Americans will experience a traumatic event in their lifetime, only 2-50%...

    Authors: Julia DiGangi, Guia Guffanti, Katie A McLaughlin and Karestan C Koenen

    Citation: Biology of Mood & Anxiety Disorders 2013 3:2

    Published on:

  4. Content type: Review

    Bipolar disorder (BD) is a multi-factorial disorder caused by genetic and environmental influences. It has a large genetic component, with heritability estimated between 59-93%. Recent genome-wide association ...

    Authors: Melanie P Leussis, Jon M Madison and Tracey L Petryshen

    Citation: Biology of Mood & Anxiety Disorders 2012 2:18

    Published on:

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