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Breast Cancer Epidemiology and Prevention

Breast Cancer Research is excited to present a curated collection on how different lifestyles, health, and populations are linked to breast cancer. Edited by one of our Deputy Editors, Dr. Leslie Bernstein is a leading epidemiologist in identifying physical activity as a means to reduce the risk of breast cancer. Dr. Bernstein would like to draw attention to two publications that come to different conclusions about the historical use of low-dose aspirin: one by Christina A. Clarke et al. and the other by Gabriella Frisk et al. We invite the reader to consider the study design and questionnaire of each cohort as well as the broader challenges of epidemiological studies. Other seminal research included in the collection is the association of breast cancer with habits such as smoking and nighttime eating as well as environmental factors such as traffic noise and air pollution.

  1. Results from previous studies indicate that use of low-dose aspirin may improve breast cancer prognosis. We evaluated aspirin use and breast cancer outcomes in relation to clinical characteristics as well as d...

    Authors: Gabriella Frisk, Sara Ekberg, Elisabet Lidbrink, Sandra Eloranta, Malin Sund, Irma Fredriksson, Mats Lambe and Karin E. Smedby
    Citation: Breast Cancer Research 2018 20:142
    Content type: Research article Published on:

  2. Exercise is an effective strategy to improve quality of life and physical fitness in breast cancer survivors; however, few studies have focused on the early survivorship period, minorities, physically inactive...

    Authors: Christina M Dieli-Conwright, Kerry S Courneya, Wendy Demark-Wahnefried, Nathalie Sami, Kyuwan Lee, Frank C Sweeney, Christina Stewart, Thomas A Buchanan, Darcy Spicer, Debu Tripathy, Leslie Bernstein and Joanne E Mortimer
    Citation: Breast Cancer Research 2018 20:124
    Content type: Research article Published on:

  3. Exposure to road traffic noise was associated with increased risk of estrogen receptor (ER)-negative (ER-) breast cancer in a previous cohort study, but not with overall or ER-positive (ER+) breast cancer, or ...

    Authors: Zorana Jovanovic Andersen, Jeanette Therming Jørgensen, Lea Elsborg, Søren Nymand Lophaven, Claus Backalarz, Jens Elgaard Laursen, Torben Holm Pedersen, Mette Kildevæld Simonsen, Elvira Vaclavik Bräuner and Elsebeth Lynge
    Citation: Breast Cancer Research 2018 20:119
    Content type: Research article Published on:

  4. Limited evidence, mostly from studies in Western populations, suggests that the prognostic effects of lifestyle-related risk factors may be molecular subtype-dependent. Here, we examined whether pre-diagnostic...

    Authors: Mustapha Abubakar, Hyuna Sung, Devi BCR, Jennifer Guida, Tieng Swee Tang, Ruth M. Pfeiffer and Xiaohong R. Yang
    Citation: Breast Cancer Research 2018 20:114
    Content type: Research article Published on:

  5. Although it has been well-documented that obesity is associated with decreased risk of premenopausal breast cancer and increased risk of postmenopausal breast cancer, it is unclear whether these associations d...

    Authors: Huiyan Ma, Giske Ursin, Xinxin Xu, Eunjung Lee, Kayo Togawa, Kathleen E. Malone, Polly A. Marchbanks, Jill A. McDonald, Michael S. Simon, Suzanne G. Folger, Yani Lu, Jane Sullivan-Halley, Dennis M. Deapen, Michael F. Press and Leslie Bernstein
    Citation: Breast Cancer Research 2018 20:5
    Content type: Research article Published on:

  6. High mammographic density is a strong, well-established breast cancer risk factor. Three studies conducted in various smaller geographic settings reported inconsistent findings between air pollution and mammog...

    Authors: Natalie C. DuPre, Jaime E. Hart, Kimberly A. Bertrand, Peter Kraft, Francine Laden and Rulla M. Tamimi
    Citation: Breast Cancer Research 2017 19:124
    Content type: Research Article Published on:

  8. Body size in early life is inversely associated with adult breast cancer (BC) risk, but it is unclear whether the associations differ by tumor characteristics.

    Authors: Md. Shajedur Rahman Shawon, Mikael Eriksson and Jingmei Li
    Citation: Breast Cancer Research 2017 19:84
    Content type: Research article Published on:

  9. Regular users of aspirin may have reduced risk of breast cancer. Few studies have addressed whether risk reduction pertains to specific breast cancer subtypes defined jointly by hormone receptor (estrogen and ...

    Authors: Christina A. Clarke, Alison J. Canchola, Lisa M. Moy, Susan L. Neuhausen, Nadia T. Chung, James V. Lacey Jr and Leslie Bernstein
    Citation: Breast Cancer Research 2017 19:52
    Content type: Research article Published on:

  10. A novel line of research suggests that eating at nighttime may have several metabolic consequences that are highly relevant to breast cancer. We investigated the association between nighttime eating habits aft...

    Authors: Mengjie Li, Lap Ah Tse, Wing-cheong Chan, Chi-hei Kwok, Siu-lan Leung, Cherry Wu, Wai-cho Yu, Priscilla Ming-yi Lee, Koon-ho Tsang, Sze-hong Law, Roel Vermeulen, Fangyi Gu, Neil E. Caporaso, Ignatius Tak-sun Yu, Feng Wang and Xiaohong Rose Yang
    Citation: Breast Cancer Research 2017 19:31
    Content type: Research article Published on:

  11. Early age at menarche, nulliparity, late age at first completed pregnancy, and never having breastfed, are established breast cancer risk factors. However, among breast cancer subtypes, it remains unclear whet...

    Authors: Huiyan Ma, Giske Ursin, Xinxin Xu, Eunjung Lee, Kayo Togawa, Lei Duan, Yani Lu, Kathleen E. Malone, Polly A. Marchbanks, Jill A. McDonald, Michael S. Simon, Suzanne G. Folger, Jane Sullivan-Halley, Dennis M. Deapen, Michael F. Press and Leslie Bernstein
    Citation: Breast Cancer Research 2017 19:6
    Content type: Research article Published on:

  12. In a recent case–control study, long-term use of calcium channel blocking drugs was associated with a greater-than-twofold increased breast cancer risk. If prospectively collected data confirm that calcium cha...

    Authors: Lauren E. Wilson, Aimee A. D’Aloisio, Dale P. Sandler and Jack A. Taylor
    Citation: Breast Cancer Research 2016 18:61
    Content type: Research article Published on: