Application of Omics/Single cell analysis in precision medicine

Multi-omics approach to precision medicine for immune-mediated diseases

Recent innovation in high-throughput sequencing technologies has drastically empowered the scientific research. Consequently, now, it is possible to capture comprehensive profiles of samples at multiple levels...

Authors: Mineto Ota and Keishi Fujio

Citation: Inflammation and Regeneration 2021 41:23

Content type: Review Published on: 1 August 2021
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Multiomic technologies for analyses of inborn errors of immunity: from snapshot of the average cell to dynamic temporal picture at single-cell resolution

Advances in DNA sequencing technology have significantly impacted human genetics; they have enabled the analysis of genetic causes of rare diseases, which are usually pathogenic variants in a single gene at th...

Authors: Yusuke Kawashima, Ryuta Nishikomori and Osamu Ohara

Citation: Inflammation and Regeneration 2021 41:19

Content type: Review Published on: 1 July 2021
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Statistical genetics and polygenic risk score for precision medicine

The prediction of disease risks is an essential part of personalized medicine, which includes early disease detection, prevention, and intervention. The polygenic risk score (PRS) has become the standard for q...

Authors: Takahiro Konuma and Yukinori Okada

Citation: Inflammation and Regeneration 2021 41:18

Content type: Review Published on: 17 June 2021
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