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Acute Kidney Injury (AKI)

Edited by Prof Michael Joannidis.

Acute kidney injury is probably the most frequent syndrome observed in critically ill patients carrying significant implications with regard to morbidity, mortality as well as long term outcome. Despite the fact that the broadly accepted KDIGO criteria published in 2012 helped to standardize diagnosis of AKI, we still have to keep in mind that this syndrome comprises very heterogeneous disease states. Thus, AKI has many facets which the clinician should be aware of when trying to optimise early diagnosis and to institute timely preventive measures as well as adequate treatment.

Critical Care is therefore introducing a series of papers covering state of the art differential diagnosis of AKI, short-term and long-term effects, and specific characteristic of this syndrome in various populations like patients with oncological/haematological diseases, liver disease or after cardiac surgery. For these specific situations both typical manifestations and treatment options are discussed. We hope that these thematic series will help the clinician in management of AKI which poses a serious threat to our patients.  

This series of articles has not been sponsored. All articles have undergone the journal’s standard peer review process overseen by the Series Editor, with final decisions made by the Editor in Chief. The Series Editor and Editor in Chief declare no competing interests.

  1. Content type: Research

    Endothelial activation and damage occur early during sepsis, with activated coagulopathy and playing a major role in the pathophysiology of sepsis-induced acute kidney injury (AKI). The aim of this study was t...

    Authors: Shinshu Katayama, Shin Nunomiya, Kansuke Koyama, Masahiko Wada, Toshitaka Koinuma, Yuya Goto, Ken Tonai and Jun Shima

    Citation: Critical Care 2017 21:229

    Published on:

  2. Content type: Review

    Acute kidney injury (AKI) is common and is associated with serious short- and long-term complications. Early diagnosis and identification of the underlying aetiology are essential to guide management. In this ...

    Authors: Marlies Ostermann and Michael Joannidis

    Citation: Critical Care 2016 20:299

    Published on:

  3. Content type: Review

    Patients with cancer represent a growing group among actual ICU admissions (up to 20 %). Due to their increased susceptibility to infectious and noninfectious complications related to the underlying cancer its...

    Authors: Norbert Lameire, Raymond Vanholder, Wim Van Biesen and Dominique Benoit

    Citation: Critical Care 2016 20:209

    Published on:

  4. Content type: Review

    Acute kidney injury (AKI) is the most common cause of organ dysfunction in critically ill adults, with a single episode of AKI, regardless of stage, carrying a significant morbidity and mortality risk. Since t...

    Authors: James F. Doyle and Lui G. Forni

    Citation: Critical Care 2016 20:188

    Published on:

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