Genome Medicine is calling for submissions to a new Collection on advances in healthy aging and age-related diseases.
As global demographics shift towards an aging population, biomedical sciences are confronted with novel challenges having to do with higher life expectancy, deterioration of health, and increased prevalence of disease. There is an unprecedented need to understand the mechanisms of aging, a complex multi-faceted process, in order to create progress towards anti-aging interventions and to prolong health span and well-being during the aging process.
This Collection aims at gathering innovative contributions that advance our understanding of the biological, molecular and medical implications of aging and their intricate interplay with well-being and age-related diseases. We encourage contributions that span a spectrum of disciplines, including but not limited to genetics, omics, biogerontology, epidemiology, research in model organisms and clinical research.
Topics of interest for this collection include, but are not limited to:
- Mechanisms of aging: multi-omics of aging, mitochondrial involvement in aging, epigenetic clocks, senescence, stemness, epidemiology of long-lived individuals
- Healthy aging: interventions to extend lifespan and healthspan, longevity medicine, gerotherapeutics, models of aging including model organisms
- Age-related conditions and diseases: Genetic factors in age-related diseases, neurodegeneration, cardiovascular diseases, cancer, chronic diseases, immune aging, inflammaging
- Clinical approaches: Diagnostic and clinical tools for regenerative medicine
- Environmental factors modulating the aging process: dietary interventions, physical activity, microbiome
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