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Aging and Cellular Fate: Senescence, Death, or Cancer

Edited by:
Cristophe Nicot
, PhD, Kansas University Medical Center, United States of America

Submission Status: Open   |   Submission Deadline: 31 October 2024


Molecular Cancer is calling for submissions to our Collection on 'Aging and Cellular Fate: Senescence, Death, or Cancer.'

This Collection aims to unravel complex interplay between cellular aging processes, such as senescence and apoptosis, and their impact on cancer initiation, progression, and therapeutic responses.

About the collection

Molecular Cancer is calling for submissions to our Collection on 'Aging and Cellular Fate: Senescence, Death, or Cancer.'

This Collection aims to unravel complex interplay between cellular aging processes, such as senescence and apoptosis, and their impact on cancer initiation, progression, and therapeutic responses. We welcome original research, reviews shedding light on the molecular mechanisms underlying these cellular decisions and their roles in aging and cancer diseases, and their potential manipulation for therapeutic interventions. 

Image credit: © Gabriel / Generated with AI / Stock.adobe.com

  1. Intestinal metaplasia (IM) is classified into complete intestinal metaplasia (CIM) and incomplete intestinal metaplasia (IIM). Patients diagnosed with IIM face an elevated susceptibility to the development of ...

    Authors: Hongfa Wei, Wenchao Li, Leli Zeng, Ni Ding, Kuan Li, Hong Yu, Fei Jiang, Haofan Yin, Yu Xia, Cuncan Deng, Nan Cai, Xiancong Chen, Liang Gu, Huanjie Chen, Feiran Zhang, Yulong He…
    Citation: Molecular Cancer 2024 23:124
  2. Metastasis remains the principal cause of cancer-related lethality despite advancements in cancer treatment. Dysfunctional epigenetic alterations are crucial in the metastatic cascade. Among these, super-enhan...

    Authors: Shenglan Liu, Wei Dai, Bei Jin, Feng Jiang, Hao Huang, Wen Hou, Jinxia Lan, Yanli Jin, Weijie Peng and Jingxuan Pan
    Citation: Molecular Cancer 2024 23:122
  3. Aging and cancer exhibit apparent links that we will examine in this review. The null hypothesis that aging and cancer coincide because both are driven by time, irrespective of the precise causes, can be confr...

    Authors: Léa Montégut, Carlos López-Otín and Guido Kroemer
    Citation: Molecular Cancer 2024 23:106
  4. CDC6 is an oncogenic protein whose expression level fluctuates during the cell cycle. Although several E3 ubiquitin ligases responsible for the ubiquitin-mediated proteolysis of CDC6 have been identified, the ...

    Authors: Jianfeng Cui, Xiaochen Liu, Qinghong Shang, Shuna Sun, Shouzhen Chen, Jianping Dong, Yaofeng Zhu, Lei Liu, Yangyang Xia, Yong Wang, Lu Xiang, Bowen Fan, Jiafeng Zhan, Yadi Zhou, Pengxiang Chen, Renchang Zhao…
    Citation: Molecular Cancer 2024 23:86
  5. The cell cycle is a crucial biological process that is involved in cell growth, development, and reproduction. It can be divided into G1, S, G2, and M phases, and each period is closely regulated to ensure the...

    Authors: Yuqin Xu, Yue Jiao, Chengbin Liu, Rui Miao, Chunyan Liu, Yilong Wang, Chunming Ma and Jiao Liu
    Citation: Molecular Cancer 2024 23:84
  6. Cellular senescence frequently occurs during anti-cancer treatment, and persistent senescent tumor cells (STCs) unfavorably promote tumor progression through paracrine secretion of the senescence-associated se...

    Authors: Dan Zhang, Jian-Wei Zhang, Hui Xu, Xin Chen, Yu Gao, Huan-Gang Jiang, You Wang, Han Wu, Lei Yang, Wen-Bo Wang, Jing Dai, Ling Xia, Jin Peng and Fu-Xiang Zhou
    Citation: Molecular Cancer 2024 23:70
  7. Cancer progression is continuously controlled by the immune system which can identify and destroy nascent tumor cells or inhibit metastatic spreading. However, the immune system and its deregulated activity in...

    Authors: Alessandra Zingoni, Fabrizio Antonangeli, Silvano Sozzani, Angela Santoni, Marco Cippitelli and Alessandra Soriani
    Citation: Molecular Cancer 2024 23:68

Submission Guidelines

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This Collection welcomes submission of original Research Articles. 

Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Aging and Cellular Fate: Senescence, Death, or Cancer" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.