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Alzheimer's Disease: Challenges for the next decade

Neuron cell system shown in blue

  1. Investigations of apolipoprotein E (APOE) gene, the major genetic risk modifier for Alzheimer’s disease (AD), have yielded significant insights into the pathogenic mechanism. Among the three common coding variant...

    Authors: Zonghua Li, Francis Shue, Na Zhao, Mitsuru Shinohara and Guojun Bu

    Citation: Molecular Neurodegeneration 2020 15:63

    Content type: Review

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  2. Subjective cognitive decline (SCD) is regarded as the first clinical manifestation in the Alzheimer’s disease (AD) continuum. Investigating populations with SCD is important for understanding the early patholo...

    Authors: Xiaoqi Wang, Weijie Huang, Li Su, Yue Xing, Frank Jessen, Yu Sun, Ni Shu and Ying Han

    Citation: Molecular Neurodegeneration 2020 15:55

    Content type: Review

    Published on:

  3. Alzheimer disease (AD) is the most prominent form of dementia and the 5th leading cause of death in individuals over 65. AD is a complex disease stemming from genetic, environmental, and lifestyle factors. It ...

    Authors: Hannah R. Bulgart, Evan W. Neczypor, Loren E. Wold and Amy R. Mackos

    Citation: Molecular Neurodegeneration 2020 15:42

    Content type: Review

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  4. Alzheimer’s disease (AD) is the most common neurodegenerative disorder seen in age-dependent dementia. There is currently no effective treatment for AD, which may be attributed in part to lack of a clear under...

    Authors: Tiantian Guo, Denghong Zhang, Yuzhe Zeng, Timothy Y. Huang, Huaxi Xu and Yingjun Zhao

    Citation: Molecular Neurodegeneration 2020 15:40

    Content type: Review

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  5. Alzheimer’s disease (AD) is one of the most prevalent neurodegenerative diseases, characterized by impaired cognitive function due to progressive loss of neurons in the brain. Under the microscope, neuronal ac...

    Authors: Wenzhang Wang, Fanpeng Zhao, Xiaopin Ma, George Perry and Xiongwei Zhu

    Citation: Molecular Neurodegeneration 2020 15:30

    Content type: Review

    Published on: