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Featured articles   Open Access

Trials 2009, 10:52
Although most trials published in six major journals reported post-randomization participant flow in line with the CONSORT guidelines, many reports omitted pre-randomization data, with 40% not including numbers assessed for eligibility.
Image: ORNL, Public domain
BMC Biology 2009, 7:38
Expression of PPAR gamma, an important regulator of adipocyte differentiation and expression, is repressed by methylation, which is increased in mouse models of diabetes.
Genome Biology 2009, 10:R73
A map of transcription start sites across the Drosophila genome, providing insights into initiation patterns and spatiotemporal conditions.
Image: Wikicommons, Creative Commons license 1.0, by Aaron Logan
BMC Biology 2009, 7:37
Healthy young mice treated with erythropoietin show lasting improved performance in learning and attention tasks.
Trials 2009, 10:50
Intravenous fluid restriction following major abdominal surgery may increase serious postoperative complications and length of hospital stay, finds a randomised controlled trial, terminated prematurely following interim analysis.

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