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Structural and functional annotation of the porcine immunome
Harry D Dawson, Jane E Loveland, Géraldine Pascal, James GR Gilbert, Hirohide Uenishi, Katherine M Mann, Yongming Sang, Jie Zhang, Denise Carvalho-Silva, Toby Hunt, Matthew Hardy, Zhiliang Hu, Shu-Hong Zhao, Anna Anselmo, Hiroki Shinkai, Celine Chen, Bouabid Badaoui, Daniel Berman, Clara Amid, Mike Kay, David Lloyd, Catherine Snow, Takeya Morozumi, Ryan Pei-Yen Cheng, Megan Bystrom, Ronan Kapetanovic, John C Schwartz, Ranjit Kataria, Matthew Astley, Eric Fritz et al.
BMC Genomics 2013, 14:332 (15 May 2013)
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Regions of XY homology in the pig X chromosome and the boundary of the pseudoautosomal region
Benjamin M Skinner, Kim Lachani, Carole A Sargent, Nabeel A Affara BMC Genetics 2013, 14:3 (15 January 2013)
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A de novo germline mutation in MYH7 causes a progressive dominant myopathy in pigs
Leonardo Murgiano, Imke Tammen, Barbara Harlizius, Cord Drögemüller BMC Genetics 2012, 13:99 (15 November 2012)
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Editor’s summary
A spontaneous mutation in the porcine MYH7 gene is identified as the causative mutation for Campus syndrome in pigs, representing the first case of a disorder caused by a mutation in this gene in a non-human mammalian species.
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Genome-level identification, gene expression, and comparative analysis of porcine β-defensin genes
Min-Kyeung Choi, Minh Le, Dinh Nguyen, Hojun Choi, Won Kim, Jin-Hoi Kim, Jungwan Chun, Jiyeon Hyeon, Kunho Seo, Chankyu Park BMC Genetics 2012, 13:98 (15 November 2012)
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Comparative analysis of beta-defensin genes in the pig genome shows structural conservation of syntenic regions compared with humans and cattle, with 29 porcine beta-defensin (pBD) genelike sequences identified, 17 of which are previously unreported in the porcine genome.
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A gene expression atlas of the domestic pig
Tom C Freeman, Alasdair Ivens, J Kenneth Baillie, Dario Beraldi, Mark W Barnett, David Dorward, Alison Downing, Lynsey Fairbairn, Ronan Kapetanovic, Sobia Raza, Andru Tomoiu, Ramiro Alberio, Chunlei Wu, Andrew I Su, Kim M Summers, Christopher K Tuggle, Alan L Archibald, David A Hume BMC Biology 2012, 10:90 (15 November 2012)
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Editor’s summary
A genome-wide transcriptional analysis of over 60 tissues of the domestic pig identifies a network of transcription factors functioning in gastrointestinal development, as part of a collection of BioMed Central papers accompanying the publication of the pig genome in Nature.
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A high density recombination map of the pig reveals a correlation between sex-specific recombination and GC content
Flavie Tortereau, Bertrand Servin, Laurent Frantz, Hendrik-Jan Megens, Denis Milan, Gary Rohrer, Ralph Wiedmann, Jonathan Beever, Alan L Archibald, Lawrence B Schook, Martien AM Groenen BMC Genomics 2012, 13:586 (15 November 2012)
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High-resolution autosomal radiation hybrid maps of the pig genome and their contribution to the genome sequence assembly
Bertrand Servin, Thomas Faraut, Nathalie Iannuccelli, Diana Zelenika, Denis Milan BMC Genomics 2012, 13:585 (15 November 2012)
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High density radiation hybrid maps of the pig genome were constructed by SNP array genotyping to provide accurate physical maps for each pig autosome and were used to identify problems and aid genome assembly.
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The complete swine olfactory subgenome: expansion of the olfactory gene repertoire in the pig genome
Dinh Nguyen, Kyooyeol Lee, Hojun Choi, Min-kyeung Choi, Minh Le, Ning Song, Jin-Hoi Kim, Han Seo, Jae-Wook Oh, Kyungtae Lee, Tae-Hun Kim, Chankyu Park BMC Genomics 2012, 13:584 (15 November 2012)
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A genome wide association study for backfat thickness in Italian Large White pigs highlights new regions affecting fat deposition including neuronal genes
Luca Fontanesi, Giuseppina Schiavo, Giuliano Galimberti, Daniela Calò, Emilio Scotti, Pier Martelli, Luca Buttazzoni, Rita Casadio, Vincenzo Russo BMC Genomics 2012, 13:583 (15 November 2012)
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Genotyping in Italian Large White pigs finds association of SNPs and genes with backfat thickness, and Gene Ontology terms associated with significant markers match findings from previous studies of human obesity.
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First survey and functional annotation of prohormone and convertase genes in the pig
Kenneth I Porter, Bruce R Southey, Jonathan V Sweedler, Sandra L Rodriguez-Zas BMC Genomics 2012, 13:582 (15 November 2012)
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Large-scale sequencing based on full-length-enriched cDNA libraries in pigs: contribution to annotation of the pig genome draft sequence
Hirohide Uenishi, Takeya Morozumi, Daisuke Toki, Tomoko Eguchi-Ogawa, Lauretta A Rund, Lawrence B Schook BMC Genomics 2012, 13:581 (15 November 2012)
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Development of a genetic tool for product regulation in the diverse British pig breed market
Samantha Wilkinson, Alan L Archibald, Chris S Haley, Hendrik-Jan Megens, Richard PMA Crooijmans, Martien AM Groenen, Pamela Wiener, Rob Ogden BMC Genomics 2012, 13:580 (15 November 2012)
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Completion of the swine genome will simplify the production of swine as a large animal biomedical model
Eric M Walters, Eckhard Wolf, Jeffery J Whyte, Jiude Mao, Simone Renner, Hiroshi Nagashima, Eiji Kobayashi, Jianguo Zhao, Kevin D Wells, John K Critser, Lela K Riley, Randall S Prather BMC Medical Genomics 2012, 5:55 (15 November 2012)
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Editor’s summary
Eric M Walters and colleagues review the pig as a large animal biomedical model and how the publication of the swine genome sequence will further advance its utility for understanding human disease, transgenesis and xenotransplantation.
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Interphase chromosome positioning in in vitro porcine cells and ex vivo porcine tissues
Helen A Foster, Darren K Griffin, Joanna M Bridger BMC Cell Biology 2012, 13:30 (15 November 2012)
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The porcine genome is non-randomly organised with most chromosomes occupying similar nuclear positions despite developmental origin or lineage and regardless of being cultured in vitro or from in vivo tissue.
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The sequence and analysis of a Chinese pig genome
Xiaodong Fang, Yulian Mou, Zhiyong Huang, Yong Li, Lijuan Han, Yanfeng Zhang, Yue Feng, Yuanxin Chen, Xuanting Jiang, Wei Zhao, Xiaoqing Sun, Zhiqiang Xiong, Lan Yang, Huan Liu, Dingding Fan, Likai Mao, Lijie Ren, Chuxin Liu, Juan Wang, Kui Li, Guangbiao Wang, Shulin Yang, Liangxue Lai, Guojie Zhang, Yingrui Li, Jun Wang, Lars Bolund, Huanming Yang, Jian Wang, Shutang Feng, Songgang Li, Yutao Du et al.
GigaScience 2012, 1:16 (15 November 2012)
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An important model organism for medical research, the genome of the Wuzhishan inbred miniature pig is presented along with analysis of its unusual genetic features
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