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Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling.
Boileau C, Tat SK, Pelletier JP, Cheng S, Martel-Pelletier J
Arthritis Res Ther 2008, 10:R71
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