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Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress.
Ralser M, Wamelink MM, Kowald A, Gerisch B, Heeren G, Struys EA, Klipp E, Jakobs C, Breitenbach M, Lehrach H, Krobitsch S
J Biol 2007 Dec 21, 6:10
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A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth.
Ralser M, Wamelink MM, Struys EA, Joppich C, Krobitsch S, Jakobs C, Lehrach H
Proc Natl Acad Sci U S A 2008 Nov 18, 105:17807-11
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Activity motifs reveal principles of timing in transcriptional control of the yeast metabolic network.
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Interfering with glycolysis causes Sir2-dependent hyper-recombination of Saccharomyces cerevisiae plasmids.
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