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LEDGF/p75 has increased expression in blasts from chemotherapy-resistant human acute myelogenic leukemia patients and protects leukemia cells from apoptosis in vitro.
Huang TS, Myklebust LM, Kjarland E, Gjertsen BT, Pendino F, Bruserud , Døskeland SO, Lillehaug JR
Mol Cancer
2007,
6
:31
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PubMed Central articles that cite the above article:
1.
Menin critically links MLL proteins with LEDGF on cancer-associated target genes.
Yokoyama A, Cleary ML
Cancer Cell
2008 Jul 8,
14
:36-46
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2.
IL-3 and oncogenic Abl regulate the myeloblast transcriptome by altering mRNA stability.
Ernst J, Ghanem L, Bar-Joseph Z, McNamara M, Brown J, Steinman RA
PLoS One
2009,
4
:e7469
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