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Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation.
Uller L, Mathiesen JM, Alenmyr L, Korsgren M, Ulven T, Högberg T, Andersson G, Persson CG, Kostenis E
Respir Res 2007, 8:16
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The roles of the prostaglandin D(2) receptors DP(1) and CRTH2 in promoting allergic responses.
Pettipher R
Br J Pharmacol 2008 Mar, 153 Suppl 1:S191-9
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CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation.
Lukacs NW, Berlin AA, Franz-Bacon K, Sásik R, Sprague LJ, Ly TW, Hardiman G, Boehme SA, Bacon KB
Am J Physiol Lung Cell Mol Physiol 2008 Nov, 295:L767-79
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