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Methotrexate in rheumatoid arthritis is frequently effective, even if re-employed after a previous failure.
Kapral T, Stamm T, Machold KP, Montag K, Smolen JS, Aletaha D
Arthritis Res Ther 2006, 8:R46
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Functional improvement after patients with rheumatoid arthritis start a new disease modifying antirheumatic drug (DMARD) associated with frequent changes in DMARD: the CORRONA database.
Ranganath VK, Paulus HE, Onofrei A, Khanna D, Reed G, Elashoff DA, Kremer JM, Furst DE
J Rheumatol 2008 Oct, 35:1966-71
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