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PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the disease.
Johansson M, Arlestig L, Hallmans G, Rantapää-Dahlqvist S
Arthritis Res Ther 2006, 8:R19
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The MHC2TA -168A>G gene polymorphism is not associated with rheumatoid arthritis in Austrian patients.
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Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene.
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