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The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage.
Bekpen C, Hunn JP, Rohde C, Parvanova I, Guethlein L, Dunn DM, Glowalla E, Leptin M, Howard JC
Genome Biol
2005,
6
:R92
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PubMed Central articles that cite the above article:
1.
The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice.
Bernstein-Hanley I, Coers J, Balsara ZR, Taylor GA, Starnbach MN, Dietrich WF
Proc Natl Acad Sci U S A
2006 Sep 19,
103
:14092-7
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2.
Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii.
Hunn JP, Koenen-Waisman S, Papic N, Schroeder N, Pawlowski N, Lange R, Kaiser F, Zerrahn J, Martens S, Howard JC
EMBO J
2008 Oct 8,
27
:2495-509
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3.
The gamma interferon (IFN-gamma)-inducible GTP-binding protein IGTP is necessary for toxoplasma vacuolar disruption and induces parasite egression in IFN-gamma-stimulated astrocytes.
Melzer T, Duffy A, Weiss LM, Halonen SK
Infect Immun
2008 Nov,
76
:4883-94
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4.
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.
Parkes M, Barrett JC, Prescott NJ, Tremelling M, Anderson CA, Fisher SA, Roberts RG, Nimmo ER, Cummings FR, Soars D, Drummond H, Lees CW, Khawaja SA, Bagnall R, Burke DA, Todhunter CE, Ahmad T, Onnie CM, McArdle W, Strachan D, Bethel G, Bryan C, Lewis CM, Deloukas P, Forbes A, Sanderson J, Jewell DP, Satsangi J, Mansfield JC, Wellcome Trust Case Control Consortium , Cardon L, Mathew CG
Nat Genet
2007 Jul,
39
:830-2
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5.
Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death.
Zhao YO, Khaminets A, Hunn JP, Howard JC
PLoS Pathog
2009 Feb,
5
:e1000288
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Death and resurrection of the human IRGM gene.
Bekpen C, Marques-Bonet T, Alkan C, Antonacci F, Leogrande MB, Ventura M, Kidd JM, Siswara P, Howard JC, Eichler EE
PLoS Genet
2009 Mar,
5
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7.
Modeling infectious disease in mice: co-adaptation and the role of host-specific IFNgamma responses.
Coers J, Starnbach MN, Howard JC
PLoS Pathog
2009 May,
5
:e1000333
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8.
Emerging themes in IFN-gamma-induced macrophage immunity by the p47 and p65 GTPase families.
Shenoy AR, Kim BH, Choi HP, Matsuzawa T, Tiwari S, MacMicking JD
Immunobiology
2007,
212
:771-84
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9.
Human guanylate binding proteins potentiate the anti-chlamydia effects of interferon-gamma.
Tietzel I, El-Haibi C, Carabeo RA
PLoS One
2009,
4
:e6499
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10.
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease.
McCarroll SA, Huett A, Kuballa P, Chilewski SD, Landry A, Goyette P, Zody MC, Hall JL, Brant SR, Cho JH, Duerr RH, Silverberg MS, Taylor KD, Rioux JD, Altshuler D, Daly MJ, Xavier RJ
Nat Genet
2008 Sep,
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:1107-12
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11.
Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains.
Intemann CD, Thye T, Niemann S, Browne EN, Amanua Chinbuah M, Enimil A, Gyapong J, Osei I, Owusu-Dabo E, Helm S, Rüsch-Gerdes S, Horstmann RD, Meyer CG
PLoS Pathog
2009 Sep,
5
:e1000577
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12.
Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis.
Xavier RJ, Huett A, Rioux JD
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Genome-wide association studies: a new window into immune-mediated diseases.
Xavier RJ, Rioux JD
Nat Rev Immunol
2008 Aug,
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14.
Rapid elimination of Toxoplasma gondii by gamma interferon-primed mouse macrophages is independent of CD40 signaling.
Zhao Y, Wilson D, Matthews S, Yap GS
Infect Immun
2007 Oct,
75
:4799-803
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15.
Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages.
Ling YM, Shaw MH, Ayala C, Coppens I, Taylor GA, Ferguson DJ, Yap GS
J Exp Med
2006 Sep 4,
203
:2063-71
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16.
*** Unable to retrieve article 18772884 ***
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