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Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice.
Heneka MT, Sastre M, Dumitrescu-Ozimek L, Dewachter I, Walter J, Klockgether T, Van Leuven F
J Neuroinflammation 2005 Oct 7, 2:22
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PubMed Central articles that cite the above article:

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The Basic Biology of BACE1: A Key Therapeutic Target for Alzheimer's Disease.
Cole SL, Vassar R
Curr Genomics 2007 Dec, 8:509-30
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