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The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles.
Wilkins A, Szafranski K, Fraser DJ, Bakthavatsalam D, Müller R, Fisher PR, Glöckner G, Eichinger L, Noegel AA, Insall RH
Genome Biol
2005,
6
:R68
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PubMed Central articles that cite the above article:
1.
Cyclic AMP signalling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs.
Kae H, Kortholt A, Rehmann H, Insall RH, Van Haastert PJ, Spiegelman GB, Weeks G
EMBO Rep
2007 May,
8
:477-82
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Phosphoinositide 3-kinase activity controls the chemoattractant-mediated activation and adaptation of adenylyl cyclase.
Comer FI, Parent CA
Mol Biol Cell
2006 Jan,
17
:357-66
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3.
Linking Ras to myosin function: RasGEF Q, a Dictyostelium exchange factor for RasB, affects myosin II functions.
Mondal S, Bakthavatsalam D, Steimle P, Gassen B, Rivero F, Noegel AA
J Cell Biol
2008 Jun 2,
181
:747-60
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