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The evolution of drug-activated nuclear receptors: one ancestral gene diverged into two xenosensor genes in mammals.
Handschin C, Blättler S, Roth A, Looser R, Oscarson M, Kaufmann MR, Podvinec M, Gnerre C, Meyer UA
Nucl Recept
2004 Oct 12,
2
:7
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1.
Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds.
Reschly EJ, Krasowski MD
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2006 May,
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Evolution of the pregnane x receptor: adaptation to cross-species differences in biliary bile salts.
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Activation of steroid and xenobiotic receptor (SXR, NR1I2) and its orthologs in laboratory, toxicologic, and genome model species.
Milnes MR, Garcia A, Grossman E, Grün F, Shiotsugu J, Tabb MM, Kawashima Y, Katsu Y, Watanabe H, Iguchi T, Blumberg B
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2008 Jul,
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Regulatory mechanisms to control tissue alpha-tocopherol.
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