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The active metabolite of leflunomide, A77 1726, increases the production of IL-1 receptor antagonist in human synovial fibroblasts and articular chondrocytes.
Palmer G, Burger D, Mezin F, Magne D, Gabay C, Dayer JM, Guerne PA
Arthritis Res Ther 2004, 6:R181-9
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Expression and function of junctional adhesion molecule-C in human and experimental arthritis.
Palmer G, Busso N, Aurrand-Lions M, Talabot-Ayer D, Chobaz-Péclat V, Zimmerli C, Hammel P, Imhof BA, Gabay C
Arthritis Res Ther 2007, 9:R65
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