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An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets.
Zeller KI, Jegga AG, Aronow BJ, O'Donnell KA, Dang CV
Genome Biol
2003,
4
:R69
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PubMed Central articles that cite the above article:
1.
Promoter-binding and repression of PDGFRB by c-Myc are separable activities.
Mao DY, Barsyte-Lovejoy D, Ho CS, Watson JD, Stojanova A, Penn LZ
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Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays.
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Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity.
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In silico identification of transcriptional regulators associated with c-Myc.
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Identification of novel Myc target genes with a potential role in lymphomagenesis.
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Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxes.
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Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis.
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Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development.
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2005 Aug 16,
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hnRNP K binds a core polypyrimidine element in the eukaryotic translation initiation factor 4E (eIF4E) promoter, and its regulation of eIF4E contributes to neoplastic transformation.
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The Myc target gene JPO1/CDCA7 is frequently overexpressed in human tumors and has limited transforming activity in vivo.
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Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis.
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A conserved Myc protein domain, MBIV, regulates DNA binding, apoptosis, transformation, and G2 arrest.
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Myc influences global chromatin structure.
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Integration of genome and chromatin structure with gene expression profiles to predict c-MYC recognition site binding and function.
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c-Myc mediates pre-TCR-induced proliferation but not developmental progression.
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N-myc coordinates retinal growth with eye size during mouse development.
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Nuclear receptor hepatocyte nuclear factor 4alpha1 competes with oncoprotein c-Myc for control of the p21/WAF1 promoter.
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c-Myc and caspase-2 are involved in activating Bax during cytotoxic drug-induced apoptosis.
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Combined analysis of murine and human microarrays and ChIP analysis reveals genes associated with the ability of MYC to maintain tumorigenesis.
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G1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemia.
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Global regulation of nucleotide biosynthetic genes by c-Myc.
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Identification of functional networks of estrogen- and c-Myc-responsive genes and their relationship to response to tamoxifen therapy in breast cancer.
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High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma.
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Optimization of experimental design parameters for high-throughput chromatin immunoprecipitation studies.
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