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The biology of the Ets1 proto-oncogene.
Dittmer J
Mol Cancer 2003 Aug 20, 2:29
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Ras/mitogen-activated protein kinase signaling activates Ets-1 and Ets-2 by CBP/p300 recruitment.
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Thymomegaly, microsplenia, and defective homeostatic proliferation of peripheral lymphocytes in p51-Ets1 isoform-specific null mice.
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The ePHD protein SPBP interacts with TopBP1 and together they co-operate to stimulate Ets1-mediated transcription.
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Caspase-1 is a direct target gene of ETS1 and plays a role in ETS1-induced apoptosis.
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