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Lipoxygenase and cyclooxygenase metabolism: new insights in treatment and chemoprevention of pancreatic cancer.
Ding XZ, Hennig R, Adrian TE
Mol Cancer 2003 Jan 7, 2:10
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1.
15-lipoxygenase-1 production is lost in pancreatic cancer and overexpression of the gene inhibits tumor cell growth.
Hennig R, Kehl T, Noor S, Ding XZ, Rao SM, Bergmann F, Fürstenberger G, Büchler MW, Friess H, Krieg P, Adrian TE
Neoplasia 2007 Nov, 9:917-26
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Convergent oxygenation of arachidonic acid by 5-lipoxygenase and cyclooxygenase-2.
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J Am Chem Soc 2006 Jan 25, 128:720-1
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BLT2 is expressed in PanINs, IPMNs, pancreatic cancer and stimulates tumour cell proliferation.
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Br J Cancer 2008 Oct 7, 99:1064-73
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