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Application of a population-based severity scoring system to individual patients results in frequent misclassification.
Booth FV, Short M, Shorr AF, Arkins N, Bates B, Qualy RL, Levy H
Crit Care 2005 Oct 5, 9:R522-9
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Commentary

Drotrecogin alfa (activated): does current evidence support treatment for any patients with severe sepsis?
Friedrich JO, Adhikari NKJ, Meade MO
Critical Care 2006, 10:145 (2 June 2006)
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