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Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage.
Wilcock DM, Rojiani A, Rosenthal A, Subbarao S, Freeman MJ, Gordon MN, Morgan D
J Neuroinflammation 2004 Dec 8, 1:24
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Review    
Cerebral amyloid angiopathy in the aetiology and immunotherapy of Alzheimer disease
Weller RO, Preston SD, Subash M, Carare RO
Alzheimer's Research & Therapy 2009, 1:6 (12 October 2009)
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Mannan-Abeta28 conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice
Petrushina I, Ghochikyan A, Mkrtichyan M, Mamikonyan G, Movsesyan N, Ajdari R, Vasilevko V, Karapetyan A, Lees A, Agadjanyan MG, Cribbs DH
Journal of Neuroinflammation 2008, 5:42 (29 September 2008)
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Successful adjuvant-free vaccination of BALB/c mice with mutated amyloid peptides
Cao C, Lin X, Wahi MM, Jackson EA, Potter H
BMC Neuroscience 2008, 9:25 (18 February 2008)
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Interleukin-1 receptor 1 knockout has no effect on amyloid deposition in Tg2576 mice and does not alter efficacy following A immunotherapy
Das P, Smithson LA, Price RW, Holloway VM, Levites Y, Chakrabarty P, Golde TE
Journal of Neuroinflammation 2006, 3:17 (26 July 2006)
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Intracranial administration of deglycosylated C-terminal-specific anti-A antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice
Carty NC, Wilcock DM, Rosenthal A, Grimm J, Pons J, Ronan V, Gottschall PE, Gordon MN, Morgan D
Journal of Neuroinflammation 2006, 3:11 (10 May 2006)
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Novel A peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease
Zhou J, Fonseca MI, Kayed R, Hernandez I, Webster SD, Yazan O, Cribbs DH, Glabe CG, Tenner AJ
Journal of Neuroinflammation 2005, 2:28 (7 December 2005)
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Commentary    
Vascular consequences of passive A immunization for Alzheimer's disease. Is avoidance of "malactivation" of microglia enough?
Barger SW
Journal of Neuroinflammation 2005, 2:2 (11 January 2005)
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