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Evolutionary rate depends on number of protein-protein interactions independently of gene expression level: response.
Bloom JD, Adami C
BMC Evol Biol 2004 Jun 1, 4:14
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Research article

Comparative analysis of the Saccharomyces cerevisiae and Caenorhabditis elegans protein interaction networks
Agrafioti I, Swire J, Abbott J, Huntley D, Butcher S, Stumpf MPH
BMC Evolutionary Biology 2005, 5:23 (18 March 2005)
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