Turn recording back on
Phosphorylation at Ser473 regulates heterochromatin protein 1 binding and corepressor function of TIF1beta/KAP1.
Chang CW, Chou HY, Lin YS, Huang KH, Chang CJ, Hsu TC, Lee SC.
BMC Mol Biol. 2008 Jul 1;9:61.
PMID: 18590578 [PubMed - indexed for MEDLINE]
Related Articles Free article in PMC
Association of the transcriptional corepressor TIF1beta with heterochromatin protein 1 (HP1): an essential role for progression through differentiation.
Cammas F, Herzog M, Lerouge T, Chambon P, Losson R.
Genes Dev. 2004 Sep 1;18(17):2147-60.
PMID: 15342492 [PubMed - indexed for MEDLINE]
Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family.
Nielsen AL, Ortiz JA, You J, Oulad-Abdelghani M, Khechumian R, Gansmuller A, Chambon P, Losson R.
EMBO J. 1999 Nov 15;18(22):6385-95.
PMID: 10562550 [PubMed - indexed for MEDLINE]
Dynamic and selective interactions of the transcriptional corepressor TIF1 beta with the heterochromatin protein HP1 isotypes during cell differentiation.
Cammas F, Janoshazi A, Lerouge T, Losson R.
Differentiation. 2007 Sep;75(7):627-37. Epub 2007 Mar 23.
PMID: 17381543 [PubMed - indexed for MEDLINE]
Related Articles
Cell differentiation induces TIF1beta association with centromeric heterochromatin via an HP1 interaction.
Cammas F, Oulad-Abdelghani M, Vonesch JL, Huss-Garcia Y, Chambon P, Losson R.
J Cell Sci. 2002 Sep 1;115(Pt 17):3439-48.
PMID: 12154074 [PubMed - indexed for MEDLINE]
The KAP1 corepressor functions to coordinate the assembly of de novo HP1-demarcated microenvironments of heterochromatin required for KRAB zinc finger protein-mediated transcriptional repression.
Sripathy SP, Stevens J, Schultz DC.
Mol Cell Biol. 2006 Nov;26(22):8623-38. Epub 2006 Sep 5.
PMID: 16954381 [PubMed - indexed for MEDLINE]
The histone subcode: poly(ADP-ribose) polymerase-1 (Parp-1) and Parp-2 control cell differentiation by regulating the transcriptional intermediary factor TIF1beta and the heterochromatin protein HP1alpha.
Quénet D, Gasser V, Fouillen L, Cammas F, Sanglier-Cianferani S, Losson R, Dantzer F.
FASEB J. 2008 Nov;22(11):3853-65. Epub 2008 Aug 1.
PMID: 18676401 [PubMed - indexed for MEDLINE]
KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Krüppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing.
Ryan RF, Schultz DC, Ayyanathan K, Singh PB, Friedman JR, Fredericks WJ, Rauscher FJ 3rd.
Mol Cell Biol. 1999 Jun;19(6):4366-78.
PMID: 10330177 [PubMed - indexed for MEDLINE]
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins.
Schultz DC, Ayyanathan K, Negorev D, Maul GG, Rauscher FJ 3rd.
Genes Dev. 2002 Apr 15;16(8):919-32.
PMID: 11959841 [PubMed - indexed for MEDLINE]
ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation.
Sgouras DN, Athanasiou MA, Beal GJ Jr, Fisher RJ, Blair DG, Mavrothalassitis GJ.
EMBO J. 1995 Oct 2;14(19):4781-93.
PMID: 7588608 [PubMed - indexed for MEDLINE]
Heterochromatin dynamics in mouse cells: interaction between chromatin assembly factor 1 and HP1 proteins.
Murzina N, Verreault A, Laue E, Stillman B.
Mol Cell. 1999 Oct;4(4):529-40.
PMID: 10549285 [PubMed - indexed for MEDLINE]
Transcriptional repression activity of PAX3 is modulated by competition between corepressor KAP1 and heterochromatin protein 1.
Hsieh MJ, Yao YL, Lai IL, Yang WM.
Biochem Biophys Res Commun. 2006 Oct 20;349(2):573-81. Epub 2006 Aug 22.
PMID: 16945326 [PubMed - indexed for MEDLINE]
Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essential.
Lechner MS, Begg GE, Speicher DW, Rauscher FJ 3rd.
Mol Cell Biol. 2000 Sep;20(17):6449-65.
PMID: 10938122 [PubMed - indexed for MEDLINE]
Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1).
Koike N, Maita H, Taira T, Ariga H, Iguchi-Ariga SM.
FEBS Lett. 2000 Feb 4;467(1):17-21.
PMID: 10664448 [PubMed - indexed for MEDLINE]
TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids.
Khetchoumian K, Teletin M, Mark M, Lerouge T, Cerviño M, Oulad-Abdelghani M, Chambon P, Losson R.
J Biol Chem. 2004 Nov 12;279(46):48329-41. Epub 2004 Aug 20.
PMID: 15322135 [PubMed - indexed for MEDLINE]
Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites.
Bártová E, Pacherník J, Kozubík A, Kozubek S.
Histochem Cell Biol. 2007 Apr;127(4):375-88. Epub 2007 Jan 5.
PMID: 17205308 [PubMed - indexed for MEDLINE]
Molecular dissection of formation of senescence-associated heterochromatin foci.
Zhang R, Chen W, Adams PD.
Mol Cell Biol. 2007 Mar;27(6):2343-58. Epub 2007 Jan 22.
PMID: 17242207 [PubMed - indexed for MEDLINE]
Isoform-specific interaction of HP1 with human TAFII130.
Vassallo MF, Tanese N.
Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):5919-24. Epub 2002 Apr 16.
PMID: 11959914 [PubMed - indexed for MEDLINE]
Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin.
Hirota T, Lipp JJ, Toh BH, Peters JM.
Nature. 2005 Dec 22;438(7071):1176-80. Epub 2005 Oct 12.
PMID: 16222244 [PubMed - indexed for MEDLINE]
HP1 modulates the transcription of cell-cycle regulators in Drosophila melanogaster.
De Lucia F, Ni JQ, Vaillant C, Sun FL.
Nucleic Acids Res. 2005 May 19;33(9):2852-8. Print 2005.
PMID: 15905474 [PubMed - indexed for MEDLINE]