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1:

Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis.

Yu J, Ni M, Xu J, Zhang H, Gao B, Gu J, Chen J, Zhang L, Wu M, Zhen S, Zhu J.

BMC Cancer. 2002 Nov 15;2:29. Epub 2002 Nov 15.

PMID: 12433278 [PubMed - indexed for MEDLINE]

3:

Association of low p16INK4a and p15INK4b mRNAs expression with their CpG islands methylation with human hepatocellular carcinogenesis.

Qin Y, Liu JY, Li B, Sun ZL, Sun ZF.

World J Gastroenterol. 2004 May 1;10(9):1276-80.

PMID: 15112341 [PubMed - indexed for MEDLINE]

4:

Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.

Xu XL, Yu J, Zhang HY, Sun MH, Gu J, Du X, Shi DR, Wang P, Yang ZH, Zhu JD.

World J Gastroenterol. 2004 Dec 1;10(23):3441-54.

PMID: 15526363 [PubMed - indexed for MEDLINE]

5:

High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B1-DNA adduct levels in human hepatocellular carcinoma.

Zhang YJ, Ahsan H, Chen Y, Lunn RM, Wang LY, Chen SY, Lee PH, Chen CJ, Santella RM.

Mol Carcinog. 2002 Oct;35(2):85-92.

PMID: 12325038 [PubMed - indexed for MEDLINE]

6:

Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling.

Lindsey JC, Lusher ME, Anderton JA, Bailey S, Gilbertson RJ, Pearson AD, Ellison DW, Clifford SC.

Carcinogenesis. 2004 May;25(5):661-8. Epub 2003 Dec 19.

PMID: 14688019 [PubMed - indexed for MEDLINE]

7:

Methylation profiling of twenty four genes and the concordant methylation behaviours of nineteen genes that may contribute to hepatocellular carcinogenesis.

Yu J, Zhang HY, Ma ZZ, Lu W, Wang YF, Zhu JD.

Cell Res. 2003 Oct;13(5):319-33.

PMID: 14672555 [PubMed - indexed for MEDLINE]

8:

Methylation status of p14ARF, p15INK4b, and p16INK4a genes in human hepatocellular carcinoma.

Fukai K, Yokosuka O, Imazeki F, Tada M, Mikata R, Miyazaki M, Ochiai T, Saisho H.

Liver Int. 2005 Dec;25(6):1209-16.

PMID: 16343074 [PubMed - indexed for MEDLINE]

9:

Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma.

Schagdarsurengin U, Wilkens L, Steinemann D, Flemming P, Kreipe HH, Pfeifer GP, Schlegelberger B, Dammann R.

Oncogene. 2003 Mar 27;22(12):1866-71.

PMID: 12660822 [PubMed - indexed for MEDLINE]

10:

Intensive hypermethylation of the CpG island of Ras association domain family 1A in hepatitis B virus-associated hepatocellular carcinomas.

Zhong S, Yeo W, Tang MW, Wong N, Lai PB, Johnson PJ.

Clin Cancer Res. 2003 Aug 15;9(9):3376-82.

PMID: 12960125 [PubMed - indexed for MEDLINE]

11:

Methylation framework of cell cycle gene inhibitors in cirrhosis and associated hepatocellular carcinoma.

Roncalli M, Bianchi P, Bruni B, Laghi L, Destro A, Di Gioia S, Gennari L, Tommasini M, Malesci A, Coggi G.

Hepatology. 2002 Aug;36(2):427-32.

PMID: 12143052 [PubMed - indexed for MEDLINE]

12:

Impaired expression and promotor hypermethylation of O6-methylguanine-DNA methyltransferase in retinoblastoma tissues.

Choy KW, Pang CP, To KF, Yu CB, Ng JS, Lam DS.

Invest Ophthalmol Vis Sci. 2002 May;43(5):1344-9.

PMID: 11980845 [PubMed - indexed for MEDLINE]

13:

CpG island methylation in Schistosoma- and non-Schistosoma-associated bladder cancer.

Gutiérrez MI, Siraj AK, Khaled H, Koon N, El-Rifai W, Bhatia K.

Mod Pathol. 2004 Oct;17(10):1268-74.

PMID: 15154012 [PubMed - indexed for MEDLINE]

14:

Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis.

Lee S, Lee HJ, Kim JH, Lee HS, Jang JJ, Kang GH.

Am J Pathol. 2003 Oct;163(4):1371-8.

PMID: 14507645 [PubMed - indexed for MEDLINE]

15:

Susceptibility of nonpromoter CpG islands to de novo methylation in normal and neoplastic cells.

Nguyen C, Liang G, Nguyen TT, Tsao-Wei D, Groshen S, Lübbert M, Zhou JH, Benedict WF, Jones PA.

J Natl Cancer Inst. 2001 Oct 3;93(19):1465-72.

PMID: 11584062 [PubMed - indexed for MEDLINE]

16:

Oligodendroglial tumors frequently demonstrate hypermethylation of the CDKN2A (MTS1, p16INK4a), p14ARF, and CDKN2B (MTS2, p15INK4b) tumor suppressor genes.

Wolter M, Reifenberger J, Blaschke B, Ichimura K, Schmidt EE, Collins VP, Reifenberger G.

J Neuropathol Exp Neurol. 2001 Dec;60(12):1170-80.

PMID: 11764089 [PubMed - indexed for MEDLINE]

17:

Methylation profile of the promoter CpG islands of 14 "drug-resistance" genes in hepatocellular carcinoma.

Ding S, Gong BD, Yu J, Gu J, Zhang HY, Shang ZB, Fei Q, Wang P, Zhu JD.

World J Gastroenterol. 2004 Dec 1;10(23):3433-40.

PMID: 15526362 [PubMed - indexed for MEDLINE]

18:

A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines.

Lind GE, Thorstensen L, Løvig T, Meling GI, Hamelin R, Rognum TO, Esteller M, Lothe RA.

Mol Cancer. 2004 Oct 11;3:28.

PMID: 15476557 [PubMed - indexed for MEDLINE]

19:

Predicting hepatocellular carcinoma by detection of aberrant promoter methylation in serum DNA.

Zhang YJ, Wu HC, Shen J, Ahsan H, Tsai WY, Yang HI, Wang LY, Chen SY, Chen CJ, Santella RM.

Clin Cancer Res. 2007 Apr 15;13(8):2378-84.

PMID: 17438096 [PubMed - indexed for MEDLINE]

20:

Correlation between methylation profile of promoter cpg islands of seven metastasis-associated genes and their expression states in six cell lines of liver origin.

Li JL, Fei Q, Yu J, Zhang HY, Wang P, Zhu JD.

Ai Zheng. 2004 Sep;23(9):985-91.

PMID: 15363188 [PubMed - indexed for MEDLINE]

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